卢旺达学龄儿童风湿性心脏瓣膜病的患病率：采用世界心脏联盟标准的超声心动图评估
Prevalence of rheumatic valvular heart disease in Rwandan school children: echocardiographic evaluation using the World Heart Federation criteria.
作者信息
Mucumbitsi J, Bulwer B, Mutesa L, Ndahindwa V, Semakula M, Rusingiza E, Arya P, Breakey S, Patton-Bolman C, Kaplan E L
机构信息
Rwandan Heart Foundation and Department of Pediatrics, King Faisal Hospital, Kigali, Rwanda.
Noninvasive Cardiovascular Research, Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
出版信息
Cardiovasc J Afr. 2017;28(5):285-292. doi: 10.5830/CVJA-2017-007. Epub 2017 Mar 1.
BACKGROUND
Rheumatic fever (RF) and rheumatic valvular heart disease (RHD) remain important medical, surgical and public health concerns in many parts of the world, especially in sub-Saharan Africa. However, there are no published data from Rwanda. We performed a RHD prevalence study in a randomly selected sample of Rwandan school children using the 2012 World Heart Federation (WHF) criteria.
METHODS
Echocardiographic assessment of 2 501 Rwandan school children from 10 schools in the Gasabo district near Kigali was carried out. Resulting data were evaluated by four experienced echocardiographers. Statistical analyses were carried out by statisticians.
RESULTS
RHD prevalence was 6.8/1 000 children examined (95% CI: 4.2/1 000-10.9/1 000). Seventeen met WHF criteria for RHD, 13 fulfilled criteria for 'borderline' RHD and four were 'definite' RHD. None of these 17 had been previously identified.
CONCLUSION
These data indicate a significant burden of RHD in Rwanda and support a need for defined public health RF control programmes in children there.
背景
在世界许多地区，尤其是撒哈拉以南非洲，风湿热（RF）和风湿性心脏瓣膜病（RHD）仍然是重要的医学、外科和公共卫生问题。然而，卢旺达尚无公开数据。我们采用2012年世界心脏联盟（WHF）标准，对卢旺达学龄儿童的随机样本进行了RHD患病率研究。
方法
对基加利附近加萨博区10所学校的2501名卢旺达学龄儿童进行了超声心动图评估。由四位经验丰富的超声心动图医师对所得数据进行评估。由统计学家进行统计分析。
结果
接受检查的儿童中RHD患病率为6.8/1000（95%CI：4.2/1000 - 10.9/1000）。17名符合WHF的RHD标准，13名符合“临界”RHD标准，4名是“确诊”RHD。这17名之前均未被确诊。
结论
这些数据表明卢旺达RHD负担沉重，支持在该国制定明确的儿童公共卫生RF控制计划。
Zotero 插件