In October 2016, the National Academies of Sciences, Engineering, and Medicine held a meeting to consider the Fourth Industrial Revolution and its implications for manufacturing, as well as its likely social and economic effects. The meeting also explored the cross-sector collaboration between government, universities, and industry needed to accommodate emerging developments in the key technologies of the Fourth Industrial Revolution, namely artificial intelligence, virtual and augmented reality, and the Internet of Things. This publication briefly summarizes the presentations and discussions from the meeting.