早期慢性阻塞性肺疾病的自然病程
Natural course of early COPD.
作者信息
Rhee Chin Kook, Kim Kyungjoo, Yoon Hyoung Kyu, Kim Jee-Ae, Kim Sang Hyun, Lee Sang Haak, Park Yong Bum, Jung Ki-Suck, Yoo Kwang Ha, Hwang Yong Il
机构信息
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St Mary's Hospital.
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yeouido St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul.
出版信息
Int J Chron Obstruct Pulmon Dis. 2017 Feb 20;12:663-668. doi: 10.2147/COPD.S122989. eCollection 2017.
BACKGROUND AND OBJECTIVE
Few studies have examined the natural course of early COPD. The aim of this study was to observe the natural course of early COPD patients. We also aimed to analyze medical utilization and costs for early COPD during a 6-year period.
METHODS
Patients with early COPD were selected from Korean National Health and Nutrition Examination Survey (KNHANES) data. We linked the KNHANES data of patients with early COPD to National Health Insurance data.
RESULTS
A total of 2,397 patients were enrolled between 2007 and 2012. The mean forced expiratory volume in 1 second (FEV) was 78.6%, and the EuroQol five dimensions questionnaire (EQ-5D) index value was 0.9. In total, 110 patients utilized health care for COPD in 2007, and this number increased to 179 in 2012. The total mean number of days used per person increased from 4.9 in 2007 to 7.8 in 2012. The total medical cost per person also increased from 248.8 US dollar (USD) in 2007 to 780.6 USD in 2013. A multiple linear regression revealed that age, lower body mass index, lower FEV (%), and lower EQ-5D score were significantly associated with medical costs.
CONCLUSION
Even in early COPD patients, some of them eventually progressed and utilized health care for COPD.
背景与目的
很少有研究探讨早期慢性阻塞性肺疾病（COPD）的自然病程。本研究的目的是观察早期COPD患者的自然病程。我们还旨在分析6年期间早期COPD的医疗利用情况和费用。
方法
从韩国国家健康与营养检查调查（KNHANES）数据中选取早期COPD患者。我们将早期COPD患者的KNHANES数据与国家健康保险数据相链接。
结果
2007年至2012年期间共纳入2397例患者。一秒用力呼气容积（FEV）的平均值为78.6%，欧洲五维健康量表（EQ-5D）指数值为0.9。2007年共有110例患者因COPD接受医疗服务，到2012年这一数字增至179例。人均使用天数的总平均值从2007年的4.9天增加到2012年的7.8天。人均医疗费用也从2007年的248.8美元增加到2013年的780.6美元。多元线性回归显示，年龄、较低的体重指数、较低的FEV（%）以及较低的EQ-5D评分与医疗费用显著相关。
结论
即使是早期COPD患者，其中一些人最终病情仍会进展并因COPD接受医疗服务。
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