Zanetti-Yabur Alana, Rizzo Amanda, Hayde Nicole, Watkins Anthony C, Rocca Juan P, Graham Jay A
Montefiore - Einstein Center for Transplantation, Montefiore Medical Center, Bronx, NY, USA.
Albert Einstein College of Medicine, Bronx, NY, USA.
Am J Surg. 2017 Oct;214(4):743-747. doi: 10.1016/j.amjsurg.2017.01.026. Epub 2017 Feb 17.
Medication non-adherence in transplant patients is a grave problem that results in increased rejection episodes, graft loss and significant morbidity.
The efficacy of users and non-users of a mobile phone application (mobile app) in promoting medication adherence was investigated. The Beliefs about Medicine Questionnaire (BMQ) and Morisky Medication Adherence Scale (MMAS-8) were used in these cohorts to assess the predilection for poor adherence. Serum tacrolimus, creatinine levels, and rejection episodes were also recorded. Lastly, the patients were tested on their recall of their immunosuppression.
Overall, patients had extremely negative beliefs about medication reflected in their tendency toward higher predicted rates of non-adherence. Interestingly, though not significant, app users had higher rates of medication recollection.
The high-risk nature of this population demands efforts to abrogate non-adherence. Caregivers are charged with the responsibility to offer patients a feasible option to safeguard treatment compliance. Mobile apps are a potentially powerful tool, which can be used to decrease non-adherence.
移植患者的用药依从性差是一个严重问题,会导致排斥反应增加、移植物丢失和显著的发病率。
研究了手机应用程序(移动应用)使用者和非使用者在促进用药依从性方面的效果。在这些队列中使用了药物信念问卷(BMQ)和莫里isky用药依从性量表(MMAS-8)来评估依从性差的倾向。还记录了血清他克莫司、肌酐水平和排斥反应发作情况。最后,测试了患者对免疫抑制治疗的记忆情况。
总体而言,患者对药物有着极其负面的信念,这体现在他们较高的不依从预测率倾向上。有趣的是,尽管不显著,但应用程序使用者的药物记忆率更高。
该人群的高风险性质要求努力消除不依从性。护理人员有责任为患者提供保障治疗依从性的可行选择。移动应用程序是一种潜在的强大工具,可用于减少不依从性。