Beidokhti Maliheh Najari, Jäger Anna K
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
J Ethnopharmacol. 2017 Apr 6;201:26-41. doi: 10.1016/j.jep.2017.02.031. Epub 2017 Mar 1.
Type 2 diabetes is the most common type of diabetes and its prevalence is rapidly increasing throughout the world. Modifications of lifestyle such as suitable diet and exercise programs along with pharmacotherapy and education of patients are beneficial therapies for patients with type 2 diabetes. The ethnopharmacological use of herbal medicines, many of them part of our diet as spices, vegetables and fruits, has been developed for the treatment of diabetes due to inexpensiveness, easy availability and few side effects.
Our aim is to present a review for researchers who are interested in the biologically active dietary plants traditionally utilized in the treatment of diabetes.
Information was obtained from a literature search of electronic databases such as Google Scholar, Pubmed, Sci Finder and Cochrane. Common and scientific name of the fruits, vegetables, beverages, oils and spices and the words 'antidiabetic', 'hypoglycemic', 'anti-hyperglycemic', 'type 2 diabetes' were used as keywords for search.
Certain fruits and vegetables are functional foods and their consumption reduces the incidence of type 2 diabetes. Hypoglycemic effects of fruits and vegetables may be due to their inducing nature on pancreatic β-cells for insulin secretion, or bioactive compounds such as flavonoids, alkaloids and anthocyanins, which act as insulin-like molecules or insulin secretagogues.
This write-up covers hypoglycemic, anti-hyperglycemic and anti-diabetic activities of some dietary fruits, vegetables, beverages, oils and spices and their active hypoglycemic constituents. Including such plant species in the diet might improve management of type 2 diabetes.
2型糖尿病是最常见的糖尿病类型,其患病率在全球范围内迅速上升。生活方式的改变,如适当的饮食和运动计划,以及药物治疗和患者教育,对2型糖尿病患者来说是有益的治疗方法。草药的民族药理学应用,其中许多作为香料、蔬菜和水果是我们饮食的一部分,因其价格低廉、易于获取且副作用少,已被用于糖尿病的治疗。
我们的目的是为对传统上用于治疗糖尿病的具有生物活性的食用植物感兴趣的研究人员提供一篇综述。
通过对谷歌学术、PubMed、Sci Finder和Cochrane等电子数据库进行文献检索获取信息。水果、蔬菜、饮料、油类和香料的通用名和学名以及“抗糖尿病”“降血糖”“抗高血糖”“2型糖尿病”等词汇被用作检索关键词。
某些水果和蔬菜是功能性食品,食用它们可降低2型糖尿病的发病率。水果和蔬菜的降血糖作用可能归因于它们对胰腺β细胞分泌胰岛素的诱导作用,或者是黄酮类、生物碱和花青素等生物活性化合物,这些化合物可作为胰岛素样分子或胰岛素促分泌剂发挥作用。
本文阐述了一些食用水果、蔬菜、饮料、油类和香料及其活性降血糖成分的降血糖、抗高血糖和抗糖尿病活性。在饮食中纳入此类植物物种可能会改善2型糖尿病的管理。