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骆驼奶粉对2型糖尿病患者的降血糖作用:一项随机、双盲、安慰剂对照试验。

Hypoglycemic effect of camel milk powder in type 2 diabetic patients: A randomized, double-blind, placebo-controlled trial.

作者信息

Zheng Yajie, Wu Fang, Zhang Ming, Fang Bing, Zhao Liang, Dong Lijie, Zhou Xiaojuan, Ge Shaoyang

机构信息

School of Food Food and Health Beijing Technology and Business University Beijing China.

Department of Nutrition and Health China Agricultural University Beijing China.

出版信息

Food Sci Nutr. 2021 Jun 29;9(8):4461-4472. doi: 10.1002/fsn3.2420. eCollection 2021 Aug.

DOI:10.1002/fsn3.2420
PMID:34401094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8358379/
Abstract

Fresh camel milk was widely accepted to help to prevent and control of diabetes, especially in Africa, Middle East, and cooler dry areas of Asia. In this study, type 2 diabetic patients were enrolled to supplement with 10 g of camel milk powder twice a day for 4 weeks ( = 14), cow milk powder served as the placebo ( = 13). It was found that camel milk supplement decreased fasting blood glucose, 2-hr postprandial blood glucose, serum content of total cholesterol, resistin, and lipocalin-2. There was also a significant increase in serum content of osteocrin, amylin, and GLP-1in camel milk group, indicating an improvement on adipose tissue and skeletal muscle. Camel milk powder supplement significantly enriched the relative abundance of and compared with cow milk after the 4-week intervention. This study suggested that camel milk powder can be used as a functional food help to treat type 2 diabetes.

摘要

新鲜骆驼奶被广泛认为有助于预防和控制糖尿病,尤其是在非洲、中东以及亚洲较凉爽干燥的地区。在本研究中,招募了2型糖尿病患者,每天两次补充10克骆驼奶粉,持续4周(n = 14),以牛奶粉作为安慰剂(n = 13)。结果发现,补充骆驼奶可降低空腹血糖、餐后2小时血糖、总胆固醇、抵抗素和脂质运载蛋白-2的血清含量。骆驼奶组的骨分泌素、胰淀素和胰高血糖素样肽-1的血清含量也显著增加,表明脂肪组织和骨骼肌有所改善。4周干预后,与牛奶相比,补充骆驼奶粉显著丰富了肠道菌群的相对丰度。本研究表明,骆驼奶粉可作为一种功能性食品,有助于治疗2型糖尿病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/83f90eb29148/FSN3-9-4461-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/d7b4f2ba72e2/FSN3-9-4461-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/3495f3df2380/FSN3-9-4461-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/5a4f36666f00/FSN3-9-4461-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/a16ad26d722f/FSN3-9-4461-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/450e031dec98/FSN3-9-4461-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/94d170144785/FSN3-9-4461-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/83f90eb29148/FSN3-9-4461-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/d7b4f2ba72e2/FSN3-9-4461-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/3495f3df2380/FSN3-9-4461-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/5a4f36666f00/FSN3-9-4461-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/a16ad26d722f/FSN3-9-4461-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/450e031dec98/FSN3-9-4461-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/94d170144785/FSN3-9-4461-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c78/8358379/83f90eb29148/FSN3-9-4461-g005.jpg

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