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空气污染、紫外线照射与皮肤癌发生:我们所知、现状以及未来可能发生的情况?

Air pollution, UV irradiation and skin carcinogenesis: what we know, where we stand and what is likely to happen in the future?

作者信息

Zegarska Barbara, Pietkun Katarzyna, Zegarski Wojciech, Bolibok Paulina, Wiśniewski Marek, Roszek Katarzyna, Czarnecka Joanna, Nowacki Maciej

机构信息

Chair of Cosmetology and Aesthetic Dermatology, Ludwik Rydygier's Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.

Chair of Cosmetology and Aesthetic Dermatology, Ludwik Rydygier's Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland; Chair and Department of Rehabilitation, Ludwik Rydygier's Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.

出版信息

Postepy Dermatol Alergol. 2017 Feb;34(1):6-14. doi: 10.5114/ada.2017.65616. Epub 2017 Feb 7.

DOI:10.5114/ada.2017.65616
PMID:28261026
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5329103/
Abstract

The link between air pollution, UV irradiation and skin carcinogenesis has been demonstrated within a large number of epidemiological studies. Many have shown the detrimental effect that UV irradiation can have on human health as well as the long-term damage which can result from air pollution, the European ESCAPE project being a notable example. In total, at present around 2800 different chemical substances are systematically released into the air. This paper looks at the hazardous impact of air pollution and UV and discusses: 1) what we know; 2) where we stand; and 3) what is likely to happen in the future. Thereafter, we will argue that there is still insufficient evidence of how great direct air pollution and UV irradiation are as factors in the development of skin carcinogenesis. However, future prospects of progress are bright due to a number of encouraging diagnostic and preventive projects in progress at the moment.

摘要

空气污染、紫外线照射与皮肤癌发生之间的联系已在大量流行病学研究中得到证实。许多研究表明紫外线照射对人类健康可能产生的有害影响以及空气污染可能造成的长期损害,欧洲的ESCAPE项目就是一个显著例子。目前,总计约有2800种不同的化学物质被系统地排放到空气中。本文探讨了空气污染和紫外线的有害影响,并讨论了:1)我们所知道的情况;2)我们目前的状况;3)未来可能发生的情况。此后,我们将论证,关于空气污染和紫外线照射作为皮肤癌发生发展因素的直接影响程度,目前仍缺乏足够证据。然而,由于目前正在进行一些令人鼓舞的诊断和预防项目,未来取得进展的前景是光明的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/500f/5329103/227fc82d3c4b/PDIA-34-29328-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/500f/5329103/227fc82d3c4b/PDIA-34-29328-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/500f/5329103/227fc82d3c4b/PDIA-34-29328-g001.jpg

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