Zadnik Vesna, Primic Zakelj Maja, Lokar Katarina, Jarm Katja, Ivanus Urska, Zagar Tina
Institute of Oncology Ljubljana, Epidemiology and Cancer Registry, Ljubljana, Slovenia.
Radiol Oncol. 2017 Feb 22;51(1):47-55. doi: 10.1515/raon-2017-0008. eCollection 2017 Mar 1.
The aim of our study was to describe cancer burden and time trends of all cancers combined, the most frequent as well as the rare cancers in Slovenia.
The principal data source was the population-based Cancer Registry of Republic of Slovenia. The cancer burden is presented by incidence and prevalence for the period 1950-2013 and by mortality for years 1985-2013. The time trends were characterized in terms of an average annual percent change estimated by the log-linear joinpoint regression. The Dyba-Hakulinen method was used for estimation of incidence in 2016 and the projections of cancer incidence for the year 2025 were calculated applying the Globocan projection software.
In recent years, near 14,000 Slovenes were diagnosed with cancer per year and just over 6,000 died; more than 94,000 people who were ever diagnosed with cancer are currently living among us. The total burden of cancer is dominated by five most common cancer sites: skin (non-melanoma), colon and rectum, lung, breast and prostate, together representing almost 60% of all new cancer cases. On average the incidence of common cancers in Slovenia is increasing for 3.0% per year in last decade, but the incidence of rare cancers is stable.
Because cancer occurs more among the elderly, and additionally more numerous post-war generation is entering this age group, it is expected that the burden of this disease will be growing further, even if the level of risk factors remains the same as today.
我们研究的目的是描述斯洛文尼亚所有癌症（包括最常见和最罕见的癌症）的负担及时间趋势。
主要数据来源是斯洛文尼亚共和国基于人群的癌症登记处。癌症负担通过1950 - 2013年期间的发病率和患病率以及1985 - 2013年期间的死亡率来呈现。时间趋势通过对数线性连接点回归估计的年均百分比变化来表征。采用迪巴 - 哈库利宁方法估计2016年的发病率，并应用Globocan预测软件计算2025年癌症发病率的预测值。
近年来，每年有近14,000名斯洛文尼亚人被诊断患有癌症，略多于6,000人死亡；目前有超过94,000名曾被诊断患有癌症的人生活在我们中间。癌症总负担由五个最常见的癌症部位主导：皮肤（非黑色素瘤）、结肠和直肠、肺、乳腺和前列腺，这五个部位共同占所有新癌症病例的近60%。在过去十年中，斯洛文尼亚常见癌症的发病率平均每年增长3.0%，但罕见癌症的发病率保持稳定。
由于癌症在老年人中更为常见，此外更多战后出生的一代人正进入这个年龄组，预计即使风险因素水平与今天相同，这种疾病的负担仍将进一步增加。
