Angeretti A, Magi M T, Merlino C, Ferrara B, Negro Ponzi A
Institute of Microbiology, Turin, Italy.
J Med Virol. 1987 Dec;23(4):345-9. doi: 10.1002/jmv.1890230406.
Virus-specific serum IgM, IgA, and IgG were detected by ELISA in sera obtained from children with rotavirus gastroenteritis and fractionated by gel filtration. Specific IgM and IgG could be easily demonstrated, whereas IgA were very low. Moreover, polymeric IgA (p-IgA) were not present, whereas in the immune response against viruses causing systemic infections, they are synthetised in large amounts.
通过酶联免疫吸附测定法(ELISA)在从轮状病毒肠胃炎患儿获取的血清中检测病毒特异性血清免疫球蛋白M(IgM)、免疫球蛋白A(IgA)和免疫球蛋白G(IgG),并通过凝胶过滤进行分级分离。可以很容易地检测到特异性IgM和IgG,而IgA含量非常低。此外,不存在聚合性IgA(p-IgA),而在针对引起全身感染的病毒的免疫反应中,它们会大量合成。