腰椎后路椎间融合术后的临床结果:皮质骨轨迹与传统椎弓根螺钉置入的比较。
Clinical Outcomes After Posterior Lumbar Interbody Fusion: Comparison of Cortical Bone Trajectory and Conventional Pedicle Screw Insertion.
作者信息
Takenaka Shota, Mukai Yoshihiro, Tateishi Kosuke, Hosono Noboru, Fuji Takeshi, Kaito Takashi
机构信息
Department of Orthopaedic Surgery, Japan Community Healthcare Organization Osaka Hospital, Fukushima.
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
出版信息
Clin Spine Surg. 2017 Dec;30(10):E1411-E1418. doi: 10.1097/BSD.0000000000000514.
STUDY DESIGN
This study is a retrospective cohort study using prospectively collected data.
OBJECTIVE
To compare the effectiveness of posterior lumbar interbody fusion (PLIF) using the cortical bone trajectory (CBT) and conventional pedicle screw (PS) techniques.
SUMMARY OF BACKGROUND DATA
There are few published studies to date comparing PLIF using CBT technique with PLIF using the conventional PS technique.
METHODS
We studied 119 consecutive patients who underwent single-level PLIF between 2010 and 2014 with a minimum 12-month follow-up. Forty-two patients underwent CBT-PLIF (the CBT group) and 77 underwent conventional PS-PLIF (the PS group). Clinical outcomes were assessed by the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ) and visual analog scale (VAS). To assess perioperative pain, a 6-point Numeric Rating Scale score and the total amount of diclofenac sodium suppositories used were recorded. The operative time and blood loss were recorded. Muscle damage was evaluated by serum creatine kinase concentrations. Fusion status was evaluated using 3-dimensional computed tomography 12 months postoperatively. We used inverse probability of treatment weighting based on the propensity score to reduce confounding factors.
RESULTS
There were no significant between-group differences in operative time or fusion rates, whereas the CBT group experienced significantly less blood loss, lower postoperative creatine kinase levels, less diclofenac sodium suppositories, and lower Numeric Rating Scale scores than the PS group did. The change in the JOABPEQ subdomain score for social life function 1 month postoperatively was the only significantly different factor among the JOABPEQ and VAS scores.
CONCLUSIONS
Both procedures were comparable in terms of clinical outcomes and fusion rates, but CBT-PLIF provided the additional benefits of less blood loss, less intraoperative muscle damage, less perioperative pain, and earlier recovery to normal activities.
研究设计
本研究为一项回顾性队列研究,使用前瞻性收集的数据。
目的
比较采用皮质骨轨迹(CBT)技术与传统椎弓根螺钉(PS)技术进行后路腰椎椎间融合术(PLIF)的有效性。
背景数据总结
迄今为止,很少有已发表的研究比较使用CBT技术的PLIF与使用传统PS技术的PLIF。
方法
我们研究了2010年至2014年间连续接受单节段PLIF且至少随访12个月的119例患者。42例患者接受CBT-PLIF(CBT组),77例接受传统PS-PLIF(PS组)。通过日本骨科协会背痛评估问卷(JOABPEQ)和视觉模拟量表(VAS)评估临床结果。为评估围手术期疼痛,记录6分数字评定量表评分和使用双氯芬酸钠栓剂的总量。记录手术时间和失血量。通过血清肌酸激酶浓度评估肌肉损伤。术后12个月使用三维计算机断层扫描评估融合状态。我们使用基于倾向评分的治疗加权逆概率来减少混杂因素。
结果
两组在手术时间或融合率方面无显著差异,而CBT组的失血量明显少于PS组,术后肌酸激酶水平更低,双氯芬酸钠栓剂使用量更少,数字评定量表评分更低。术后1个月JOABPEQ社交生活功能子域评分的变化是JOABPEQ和VAS评分中唯一显著不同的因素。
结论
两种手术在临床结果和融合率方面具有可比性,但CBT-PLIF具有额外的益处,即失血量更少、术中肌肉损伤更少、围手术期疼痛更少,以及更早恢复正常活动。