Yu W, Seo W, Tan T, Jung B, Ziaie B
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:303-306. doi: 10.1109/EMBC.2016.7590700.
This paper reports a low-cost solution to the early detection of urinary nitrite, a common surrogate for urinary tract infection (UTI). We present a facile method to fabricate a disposable and flexible colorimetric [1] nitrite sensor and its urine-activated power source [2] on a hydrophobic (wax) paper through laser-assisted patterning and lamination. Such device, integrated with interface circuitry and a Bluetooth low energy (BLE) module can be embedded onto a diaper, and transmit semi-quantitative UTI monitoring information in a point-of-care and autonomous fashion. The proposed nitrite sensing platform achieves a sensitivity of 1.35 ms/(mg/L) and a detection limit of 4 mg/L.
本文报道了一种低成本的解决方案，用于早期检测尿亚硝酸盐，这是尿路感染（UTI）的一种常见替代指标。我们提出了一种简便的方法，通过激光辅助图案化和层压技术，在疏水（蜡）纸上制造一次性柔性比色[1]亚硝酸盐传感器及其尿液激活电源[2]。这种与接口电路和蓝牙低功耗（BLE）模块集成的设备可以嵌入尿布中，并以即时护理和自主的方式传输半定量UTI监测信息。所提出的亚硝酸盐传感平台实现了1.35 ms/(mg/L)的灵敏度和4 mg/L的检测限。
