Petrichella S, Vollere L, Ferreri F, Guerra A, Maatta S, Kononen M, Di Lazzaro V, Iannello G
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:989-992. doi: 10.1109/EMBC.2016.7590868.
The co-registration of transcranial magnetic stimulation and electroencephalography (TMS-EEG) is emerging as a successful technique for causally exploring cortical mechanisms and connections. However, various artefacts could affect TMS-EEG signals. Correct artefacted channels reconstruction is crucial to obtain accurate topographical representation and consequently accurate inverse problem solution, in order to map in a proper way the global brain responses after the stimulation of one particular brain region of interest. In this paper, we discuss the problem of artefacted channels interpolation in TMS-EEG signals. Aim of the study was to investigate two different interpolation methods evaluating their performance in two datasets: one constituted by 19 EEG channels montage (low-density spatial resolution) and the other one by 60 EEG channels montage (high-density spatial resolution). In addition, these evaluations took place in two different contexts of application: after the averaging of TMS Evoked Potentials (TEPs) in a time interval to obtain a global information in the considered range, and at fixed latencies 100 ms and 300 ms after the TMS stimulus. The results showed that the global reconstruction error was lower at fixed latencies for the high-density electrodes spatial resolution montage.
经颅磁刺激与脑电图联合（TMS - EEG）登记正成为一种探索皮层机制和连接因果关系的成功技术。然而，各种伪迹可能会影响TMS - EEG信号。正确重建受伪迹影响的通道对于获得准确的地形图表示以及准确的逆问题解决方案至关重要，以便以适当的方式映射在刺激一个特定感兴趣脑区后大脑的整体反应。在本文中，我们讨论了TMS - EEG信号中受伪迹影响通道的插值问题。该研究的目的是研究两种不同的插值方法，并在两个数据集中评估它们的性能：一个由19导脑电图蒙太奇（低密度空间分辨率）组成，另一个由60导脑电图蒙太奇（高密度空间分辨率）组成。此外，这些评估在两种不同的应用场景中进行：在对一个时间间隔内的TMS诱发电位（TEP）进行平均以获得所考虑范围内的全局信息之后，以及在TMS刺激后固定潜伏期100毫秒和300毫秒时。结果表明，对于高密度电极空间分辨率蒙太奇，在固定潜伏期时全局重建误差较低。
