Miller L J, Malagelada J R, Go V L
Gut. 1978 Aug;19(8):699-706. doi: 10.1136/gut.19.8.699.
Duodenal function was studied in 11 healthy volunteers after intragastric instillation of a mixed semi-elemental meal. The duodenum accepted chyme of varying pH, osmolality, and nutrient concentration; and, as a result of biliary, pancreatic, and enteric secretion as well as absorption, it delivered chyme with nearly constant pH, osmolality, and nutrient concentration to the jejunum. The flow rate and nutrient load of jejunal chyme varied. The duodenum absorbed more carbohydrate than lipid and less protein, taking up each nutrient at a constant rate during most of the postprandial period. The percentage of nutrient load absorbed was greatest in the late postprandial period, when flow rate, nutrient load, and concentrations were low.
在11名健康志愿者经胃内灌注混合半要素膳后,对十二指肠功能进行了研究。十二指肠接纳了不同pH值、渗透压和营养物质浓度的食糜;并且,由于胆汁、胰液和肠液的分泌以及吸收作用,它将pH值、渗透压和营养物质浓度几乎恒定的食糜输送至空肠。空肠食糜的流速和营养负荷有所变化。十二指肠吸收的碳水化合物多于脂质,蛋白质吸收较少,在餐后大部分时间内以恒定速率摄取每种营养物质。在餐后后期,当流速、营养负荷和浓度较低时,营养负荷吸收的百分比最大。