Eid Yara M, Sahmoud Sahar I, Abdelsalam Mona M, Eichorst Barbara
Department of Endocrinology and Metabolism, Ain-Shams University Hospital, Cairo, Egypt.
Healthy Interactions, Chicago, IL.
Diabetes Spectr. 2017 Feb;30(1):36-42. doi: 10.2337/ds15-0058.
This study aims to assess the feasibility of promoting safe Ramadan fasting through diabetes self-management education (DSME) and to determine the effect of such education on hypoglycemic episodes.
This prospective study included subjects attending Ramadan reinforcement sessions for participants in the Educational Program for People with Diabetes (EPPWD) at the Ain-Shams University Diabetes Center in Cairo, Egypt. The DSME sessions started 2-3 weeks before Ramadan and included one experimental fasting day during the first week and one during the second week. Participants' A1C and serum fructosamine levels were measured before and after Ramadan, and they completed weekly self-monitoring of blood glucose (SMBG) logs.
Among 21 participants who were intending to fast for Ramadan, 14 completed the program. Their mean A1C was 6.7 ± 1.6%, and SMBG results showed a statistically nonsignificant difference in mean blood glucose levels before and after Ramadan (123.84 ± 39.96 and 123.84 ± 25.92 mg/dL, respectively; >0.05). Serum fructosamine after Ramadan declined by 10% from pre-Ramadan levels. The mean number of hypoglycemic events before Ramadan was 3 ± 1.04, which declined to 1.4 ± 0.5 during Ramadan. Differences between group 1 (those without hypoglycemia, = 8) and group 2 (those with hypoglycemia, = 6) were nonsignificant for all variables, including A1C.
Ramadan fasting is feasible for people with diabetes who are on a multiple daily injection insulin regimen and participate in the EPPWD. The number of hypoglycemic events per month declined with the attainment of DSME.
本研究旨在评估通过糖尿病自我管理教育(DSME)促进斋月安全禁食的可行性,并确定此类教育对低血糖发作的影响。
这项前瞻性研究纳入了在埃及开罗艾因夏姆斯大学糖尿病中心参加糖尿病患者教育项目(EPPWD)斋月强化课程的受试者。DSME课程在斋月前2 - 3周开始,包括第一周的一个实验性禁食日和第二周的一个实验性禁食日。在斋月前后测量参与者的糖化血红蛋白(A1C)和血清果糖胺水平,并让他们完成每周的血糖自我监测(SMBG)日志。
在21名打算斋月禁食的参与者中,14人完成了该项目。他们的平均A1C为6.7±1.6%,SMBG结果显示斋月前后平均血糖水平在统计学上无显著差异(分别为123.84±39.96和123.84±25.92 mg/dL;P>0.05)。斋月后的血清果糖胺水平比斋月前下降了10%。斋月前低血糖事件的平均次数为3±1.04次,斋月期间降至1.4±0.5次。第1组(无低血糖者,n = 8)和第2组(有低血糖者,n = 6)在包括A1C在内的所有变量上差异均无统计学意义。
对于接受每日多次注射胰岛素治疗方案并参加EPPWD的糖尿病患者来说,斋月禁食是可行的。通过DSME,每月低血糖事件的数量有所减少。