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成人急性白血病合并胃肠道毛霉菌病的成功治疗:病例报告及文献综述

Successful treatment of gastrointestinal mucormycosis in an adult with acute leukemia: case report and literature review.

作者信息

Alghamdi A, Lutynski A, Minden M, Rotstein C

机构信息

Division of Infectious Diseases, Department of Medicine, and.

Medical Oncology, Leukemia Service, Princess Margaret Cancer Centre, University Health Network; and.

出版信息

Curr Oncol. 2017 Feb;24(1):e61-e64. doi: 10.3747/co.24.3522. Epub 2017 Feb 27.

DOI:10.3747/co.24.3522
PMID:28270734
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5330641/
Abstract

Mucormycosis has emerged as an important cause of invasive fungal infection in patients with hematologic malignancies. Gastrointestinal mucormycosis is an unusual presentation of this invasive fungal infection, and it causes considerable morbidity and mortality. Such outcomes are due in part to a nonspecific presentation that results in delays in diagnosis and treatment. Successful treatment of gastrointestinal mucormycosis involves surgical debridement and appropriate antifungal therapy.

摘要

毛霉菌病已成为血液系统恶性肿瘤患者侵袭性真菌感染的重要原因。胃肠道毛霉菌病是这种侵袭性真菌感染的一种不寻常表现,会导致相当高的发病率和死亡率。这些结果部分归因于其非特异性表现,从而导致诊断和治疗延迟。成功治疗胃肠道毛霉菌病需要手术清创和适当的抗真菌治疗。

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本文引用的文献

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Gastrointestinal mucormycosis requiring surgery in adults with hematologic malignant tumors: literature review.成人血液系统恶性肿瘤患者发生的需要手术治疗的胃肠道毛霉病:文献综述
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Diagnosis and treatment of mucormycosis in patients with hematological malignancies: guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3).血液病患者毛霉菌病的诊断和治疗:第 3 届欧洲白血病感染会议(ECIL 3)指南。
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Mucormycosis in organ and stem cell transplant recipients.器官和干细胞移植受者中的毛霉菌病。
Clin Infect Dis. 2012 Jun;54(11):1629-36. doi: 10.1093/cid/cis195. Epub 2012 Mar 19.
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