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非法药物使用是急性腹痛型回肠毛霉病的一个危险因素。

Illicit Drug Use a Risk Factor for Ileal Mucormycosis Presenting With Acute Abdomen.

作者信息

Aruni Amaresh, Tandup Cherring, Chowdhury Anish, Roy Arindam, Jha Bhairavi

机构信息

Department of General Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, IND.

出版信息

Cureus. 2020 Dec 22;12(12):e12213. doi: 10.7759/cureus.12213.

DOI:10.7759/cureus.12213
PMID:33489620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7815263/
Abstract

Mucormycosis is a rare, life-threatening, angioinvasive opportunistic fungal infection. Most common sites involved are rhino cerebral, pulmonary, cutaneous followed by gastrointestinal. We report a successful management of rare gastrointestinal ileal mucormycosis with perforation peritonitis managed surgically. Later histopathology revealed the ileal mucormycosis with transmural necrotizing inflammation. Histopathological demonstration of the fungus in surgical specimens remains cornerstone of the diagnosis of mucormycosis in view of its non-specific symptoms, low isolation rates of mycological culture and lack of other rapid tests.

摘要

毛霉菌病是一种罕见的、危及生命的、血管侵袭性机会性真菌感染。最常受累的部位是鼻脑、肺部、皮肤,其次是胃肠道。我们报告了一例罕见的胃肠道回肠毛霉菌病伴穿孔性腹膜炎的成功手术治疗病例。随后的组织病理学显示回肠毛霉菌病伴透壁坏死性炎症。鉴于其非特异性症状、真菌培养分离率低以及缺乏其他快速检测方法,手术标本中真菌的组织病理学表现仍是毛霉菌病诊断的基石。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ab/7815263/19280dbdfe3e/cureus-0012-00000012213-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ab/7815263/799d8fe5d4fa/cureus-0012-00000012213-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ab/7815263/19280dbdfe3e/cureus-0012-00000012213-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ab/7815263/799d8fe5d4fa/cureus-0012-00000012213-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70ab/7815263/19280dbdfe3e/cureus-0012-00000012213-i02.jpg

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J Fungi (Basel). 2025 Apr 9;11(4):298. doi: 10.3390/jof11040298.
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Co-infection of intestinal tuberculosis and mucormycosis in a patient with Down syndrome: a unique case report with literature review.唐氏综合征患者合并肠结核和毛霉菌感染:一例独特病例报告并文献复习。
BMJ Case Rep. 2021 Nov 30;14(11):e244903. doi: 10.1136/bcr-2021-244903.

本文引用的文献

1
Nosocomial Jejunal Mucormycosis - an Unusual Cause of Perforation Peritonitis.医院获得性空肠毛霉菌病——一种罕见的穿孔性腹膜炎病因。
Iran J Pathol. 2017 Summer;12(3):295-300. Epub 2017 Jul 1.
2
A Young, Immunocompetent Woman with Small Bowel and Hepatic Mucormycosis Successfully Treated with Aggressive Surgical Debridements and Antifungal Therapy.一名年轻、免疫功能正常的女性,患有小肠和肝毛霉菌病,通过积极的手术清创和抗真菌治疗成功治愈。
Case Rep Infect Dis. 2017;2017:4173246. doi: 10.1155/2017/4173246. Epub 2017 Dec 24.
3
Successful treatment of gastrointestinal mucormycosis in an adult with acute leukemia: case report and literature review.
成人急性白血病合并胃肠道毛霉菌病的成功治疗:病例报告及文献综述
Curr Oncol. 2017 Feb;24(1):e61-e64. doi: 10.3747/co.24.3522. Epub 2017 Feb 27.
4
Gastrointestinal mucormycosis requiring surgery in adults with hematologic malignant tumors: literature review.成人血液系统恶性肿瘤患者发生的需要手术治疗的胃肠道毛霉病:文献综述
Surg Infect (Larchmt). 2015 Apr;16(2):194-202. doi: 10.1089/sur.2013.232. Epub 2014 Nov 18.
5
Ileal mucormycosis: a rare cause of lower gastrointestinal bleeding.回肠毛霉菌病:下消化道出血的罕见病因。
Ann Gastroenterol. 2014;27(2):169.
6
Gastrointestinal mucormycosis: an evolving disease.胃肠道毛霉病:一种不断演变的疾病。
Gastroenterol Hepatol (N Y). 2012 Feb;8(2):140-2.