Paudel Tarun, Singh Nihal, Raj Banjara Megha, Kafle Sambhu Prasad, Chandra Ghimire Yadu, Pokharel Bhesh Raj, Rawal Bir Bahadur, Badal Komal, Chaulagain Madhav, Pendse Razia, Ghimire Prakash
National Centre for AIDS and STI Control , Department of Health Services , Ministry of Health, Government of Nepal.
Communicable Diseases , WHO Country Office for Nepal , Lalitpur , Nepal.
J Virus Erad. 2016 Nov 28;2(Suppl 4):35-40. doi: 10.1016/S2055-6640(20)31099-2.
Nepal has made progress with the control of HIV infection in recent years. There have been changes in epidemiology, programme interventions in different population groups, and changes in policies over the last 10 years, particularly in diagnosis and treatment. Therefore, this review was conducted to identify the effectiveness of different interventions/policies in different sub-populations at risk, targeted towards epidemiology and treatment outcomes for those with HIV infection in Nepal.
This review was prepared based on a review of published and unpublished documents from the Nepalese HIV infection control programme, published articles in different journals, different survey reports including integrated bio-behavioural surveillance (IBBS) survey reports.
The prevalence of HIV infection among adults in 2014 was 0.20% with a progressive decreasing trend from 2005. The prevalence of HIV infection among injecting drug users (51.7% in 2005 and 6.4% in 2015 in Kathmandu valley) was relatively high in all years as compared to other risk groups. HIV infection prevalence among women attending antenatal clinics was higher in the year 2006 (0.25%) but there was a decreasing trend in the following years to 2015, when prevalence was 0.077%. Although different interventions were conducted to cover key populations at risk, the coverage in some risk population was very low. HIV testing status among the general population was very low (7.5% among males and 2.9% among females) in 2011. Only one-third of HIV-infected individuals were on ART in 2015, although this proportion has increased since 2005. The share of domestic budget among the total expenditure on HIV control program is below 15%.
There is the need for implementation of control programmes more efficiently and effectively with expanding geographical and population coverage. Surveillance systems should be strengthened to get up-to-date information for evidence-based planning and developing strategies. The domestic budget for HIV control programme should be increased to improve their sustainability.
近年来,尼泊尔在控制艾滋病毒感染方面取得了进展。在过去10年里,流行病学、针对不同人群的项目干预措施以及政策都发生了变化,尤其是在诊断和治疗方面。因此,开展本次综述旨在确定针对尼泊尔艾滋病毒感染者的不同干预措施/政策在不同高危亚人群中的有效性,这些措施/政策以流行病学和治疗结果为目标。
本综述基于对尼泊尔艾滋病毒感染控制项目已发表和未发表的文件、不同期刊上发表的文章、包括综合生物行为监测(IBBS)调查报告在内的不同调查报告的回顾编写而成。
2014年成人艾滋病毒感染率为0.20%,自2005年以来呈逐渐下降趋势。与其他风险群体相比,注射吸毒者中的艾滋病毒感染率多年来一直相对较高(加德满都谷地2005年为51.7%,2015年为6.4%)。2006年,产前诊所就诊妇女中的艾滋病毒感染率较高(0.25%),但在随后几年至2015年呈下降趋势,2015年感染率为0.077%。尽管开展了不同的干预措施以覆盖关键高危人群,但某些风险人群的覆盖率非常低。2011年,普通人群中的艾滋病毒检测率非常低(男性为7.5%,女性为2.9%)。2015年,只有三分之一的艾滋病毒感染者接受抗逆转录病毒治疗,尽管这一比例自2005年以来有所增加。艾滋病毒控制项目总支出中,国内预算所占份额低于15%。
需要更高效且有效地实施控制项目,扩大地理和人口覆盖范围。应加强监测系统,以获取最新信息,用于循证规划和制定战略。应增加艾滋病毒控制项目的国内预算,以提高其可持续性。