3rd Department of Obstetrics and Gynaecology, School of Medicine, Aristotle University of Thessaloniki, Thessaloníki, Greece.
Department of Clinical Pharmacology, School of Medicine, Aristotle University of Thessaloniki, Thessaloníki, Greece.
Arch Gynecol Obstet. 2019 Oct;300(4):849-859. doi: 10.1007/s00404-019-05270-1. Epub 2019 Aug 17.
Antenatal depression is a common mental health problem among pregnant women that negatively affects maternal and neonatal outcomes. Women with obstetric complications, defined as high-risk pregnancies, seem to be at particularly increased risk for developing depressive symptomatology. The purpose of this study was to review the prevalence of antenatal depression among pregnant women with obstetric complications and to identify possible associated factors.
A literature search was performed in the PubMed database and a scoping review was conducted to identify studies with data on the prevalence of antenatal depression and associated factors among high-risk pregnancies due to obstetric complications. The included studies were written in English and published up to 31/12/2018.
The prevalence of antenatal depression among pregnant women with high-risk pregnancies ranges from 12.5 to 44.2% among the reviewed studies. The associated factors significantly associated with antenatal depression include maternal age, maternal education, dwelling place, relationship with the partner, previous psychiatric diagnosis, perceived stress, antenatal attachment, abortion thoughts, smoking, diabetes, parity, number of pregnancies, gestational age, threatened preterm labour, preeclampsia and oligohydramnios.
Our findings indicate a high prevalence of depressive disorders in women with obstetric complications, suggesting the need for more rigorous screening among this population. The identification of associated factors also merits clinical attention. Further research is warranted to develop evidence-based effective screening strategies and relevant interventions.
产前抑郁症是孕妇中常见的心理健康问题，会对母婴结局产生负面影响。患有产科并发症（定义为高危妊娠）的女性似乎面临着更高的发展出抑郁症状的风险。本研究的目的是综述产科并发症孕妇产前抑郁症的患病率，并确定可能的相关因素。
在 PubMed 数据库中进行文献检索，并进行范围综述，以确定关于产科并发症高危妊娠中产前抑郁症患病率及相关因素的研究。纳入的研究为英文书写，并于 2018 年 12 月 31 日之前发表。
综述中的研究显示，高危妊娠孕妇产前抑郁症的患病率为 12.5%至 44.2%。与产前抑郁症显著相关的相关因素包括母亲年龄、母亲教育程度、居住地点、与伴侣的关系、既往精神科诊断、感知压力、产前依恋、堕胎想法、吸烟、糖尿病、产次、妊娠次数、孕龄、早产威胁、子痫前期和羊水过少。
我们的研究结果表明，产科并发症孕妇中抑郁障碍的患病率较高，这表明需要对这一人群进行更严格的筛查。相关因素的确定也值得临床关注。需要进一步的研究来制定基于证据的有效筛查策略和相关干预措施。
