Srinivasappa J, Garzelli C, Onodera T, Ray U, Notkins A L
Laboratory of Oral Medicine, National Institute of Dental Research, Bethesda, Maryland 20892.
Endocrinology. 1988 Feb;122(2):563-6. doi: 10.1210/endo-122-2-563.
Mice infected with reovirus type 1 developed a mild thyroiditis characterized by focal destruction of acinar tissue, infiltration of inflammatory cells, and autoantibodies to thyroglobulin and microsomal antigens. Thyroid involvement appears to be part of a more generalized virus-induced polyendocrine disease.
感染1型呼肠孤病毒的小鼠会发展出一种轻度甲状腺炎,其特征为腺泡组织的局灶性破坏、炎症细胞浸润以及针对甲状腺球蛋白和微粒体抗原的自身抗体。甲状腺受累似乎是更广泛的病毒诱导的多内分泌疾病的一部分。