Mitchell J D, Kirkham N, Machin D
J Pathol. 1984 Dec;144(4):269-73. doi: 10.1002/path.1711440408.
The presence of focal collections of lymphocytes within the thyroid gland has been associated with autoimmune thyroiditis. In a prospective study 197 thyroid glands were examined from post mortems performed in two Southampton hospitals over a 12 month period. The mean thyroid mass was 19.5 g in women and 22.2 g in men. Varying degrees of focal lymphocytic thyroiditis were present in 54 per cent of women and 24 per cent of men. Morphometry showed that on average less than 4 per cent of the gland was infiltrated by lymphocytes. There was no significant relationship with age. A possible association between focal lymphocytic thyroiditis and circulating thyroid autoantibodies has been shown.
甲状腺内淋巴细胞灶性聚集与自身免疫性甲状腺炎有关。在一项前瞻性研究中，对在南安普敦两家医院进行的为期12个月的尸检中取出的197个甲状腺进行了检查。女性甲状腺平均重量为19.5克，男性为22.2克。54%的女性和24%的男性存在不同程度的灶性淋巴细胞性甲状腺炎。形态计量学显示，平均不到4%的腺体被淋巴细胞浸润。与年龄无显著关系。已表明灶性淋巴细胞性甲状腺炎与循环甲状腺自身抗体之间可能存在关联。
