生物催化工程：全景图。
Biocatalysis engineering: the big picture.
机构信息
Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Johannesburg 2050, South Africa.
出版信息
Chem Soc Rev. 2017 May 22;46(10):2678-2691. doi: 10.1039/c6cs00854b.
In this tutorial review we describe a holistic approach to the invention, development and optimisation of biotransformations utilising isolated enzymes. Increasing attention to applied biocatalysis is motivated by its numerous economic and environmental benefits. Biocatalysis engineering concerns the development of enzymatic systems as a whole, which entails engineering its different components: substrate engineering, medium engineering, protein (enzyme) engineering, biocatalyst (formulation) engineering, biocatalytic cascade engineering and reactor engineering.
在本教程综述中，我们描述了一种整体方法，用于利用分离酶进行生物转化的发明、开发和优化。人们越来越关注应用生物催化，是因为它具有许多经济和环境效益。生物催化工程涉及整个酶系统的开发，这需要对其不同组件进行工程改造：底物工程、介质工程、蛋白质（酶）工程、生物催化剂（配方）工程、生物催化级联工程和反应器工程。
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