Institute of Organic Chemistry, RWTH Aachen University , Landoltweg 1, 52074 Aachen, Germany.
King Abdullah University of Science and Technology (KAUST)KAUST Catalysis Center (KCC) , Thuwal, 23955-6900 Saudi Arabia.
Org Lett. 2017 Apr 7;19(7):1788-1791. doi: 10.1021/acs.orglett.7b00556. Epub 2017 Mar 13.
A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.
本文描述了一种镍催化的方法，通过 C(sp)-O 键断裂，将芳基和杂芳基醇衍生物转化为伯胺和仲胺。该新的胺化反应可应用于一系列具有不同官能团的底物，并使用易得的二苯甲酮亚胺作为有效的氮源。
