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了解一项旨在改善初级医疗保健中用药安全的技术干预措施的实施与采用情况:一项实在论评价。

Understanding the implementation and adoption of a technological intervention to improve medication safety in primary care: a realist evaluation.

作者信息

Jeffries Mark, Phipps Denham L, Howard Rachel L, Avery Anthony J, Rodgers Sarah, Ashcroft Darren M

机构信息

Centre for Pharmacoepidemiology and Drug Safety, School of Health Sciences, University of Manchester, Manchester, UK.

NIHR Greater Manchester Primary Care Patient Safety Translational Research Centre, University of Manchester, Manchester Academic Health Sciences Centre (MAHSC), Manchester, UK.

出版信息

BMC Health Serv Res. 2017 Mar 14;17(1):196. doi: 10.1186/s12913-017-2131-5.

Abstract

BACKGROUND

Monitoring for potentially hazardous prescribing is increasingly important to improve medication safety. Healthcare information technology can be used to achieve this aim, for example by providing access to prescribing data through surveillance of patients' electronic health records. The aim of our study was to examine the implementation and adoption of an electronic medicines optimisation system that was intended to facilitate clinical audit in primary care by identifying patients at risk of an adverse drug event. We adopted a sociotechnical approach that focuses on how complex social, organisational and institutional factors may impact upon the use of technology within work settings.

METHODS

We undertook a qualitative realist evaluation of the use of an electronic medicines optimisation system in one Clinical Commissioning Group in England. Five semi-structured interviews, four focus groups and one observation were conducted with a range of stakeholders. Consistent with a realist evaluation methodology, the analysis focused on exploring the links between context, mechanism and outcome to explain the ways the intervention might work, for whom and in what circumstances.

RESULTS

Using the electronic medicines optimisation system could lead to a number of improved patient safety outcomes including pre-emptively reviewing patients at risk of adverse drug events. The effective use of the system depended upon engagement with the system, the flow of information between different health professionals centrally placed at the Clinical Commissioning Group and those locally placed at individual general practices, and upon variably adapting work practices to facilitate the use of the system. The use of the system was undermined by perceptions of ownership, lack of access, and lack of knowledge and awareness.

CONCLUSIONS

The use of an electronic medicines optimisation system may improve medication safety in primary care settings by identifying those patients at risk of an adverse drug event. To fully realise the potential benefits for medication safety there needs to be better utilisation across primary care and with a wider range of stakeholders. Engaging with all potential stakeholders and users prior to implementation of such systems might allay perceptions that the system is owned centrally and increase knowledge of the potential benefits.

摘要

背景

监测潜在的危险处方对于提高用药安全性愈发重要。医疗信息技术可用于实现这一目标,例如通过监测患者的电子健康记录来获取处方数据。我们研究的目的是考察一个电子药物优化系统的实施与采用情况,该系统旨在通过识别有药物不良事件风险的患者来促进初级保健中的临床审计。我们采用了一种社会技术方法,该方法关注复杂的社会、组织和制度因素如何可能影响工作环境中技术的使用。

方法

我们对英格兰一个临床委托小组中电子药物优化系统的使用进行了定性现实主义评估。与一系列利益相关者进行了五次半结构化访谈、四次焦点小组讨论和一次观察。与现实主义评估方法一致,分析重点在于探索背景、机制和结果之间的联系,以解释干预措施可能起作用的方式、针对哪些人以及在何种情况下起作用。

结果

使用电子药物优化系统可带来一些改善患者安全的结果,包括对有药物不良事件风险的患者进行预先审查。该系统的有效使用取决于对系统的参与度、临床委托小组中集中办公的不同医疗专业人员与各个基层医疗诊所中本地办公的人员之间的信息流,以及根据情况灵活调整工作流程以促进系统的使用。对所有权的认知、获取权限的缺乏以及知识和意识的欠缺削弱了该系统的使用。

结论

使用电子药物优化系统可能通过识别有药物不良事件风险的患者来提高初级保健环境中的用药安全性。为了充分实现用药安全方面的潜在益处,需要在初级保健中以及与更广泛的利益相关者之间更好地利用该系统。在实施此类系统之前与所有潜在的利益相关者和用户进行接触,可能会消除认为系统由中央掌控的看法,并增加对潜在益处的了解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46f4/5348746/837b6cad738d/12913_2017_2131_Fig1_HTML.jpg

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