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自动通知系统对病房恶化患者的临床结局的影响。

Effect of an automated notification system for deteriorating ward patients on clinical outcomes.

机构信息

Respiratory & Critical Care Medicine, Bangor University & Ysbyty Gwynedd, Bangor, LL57 2PW, Wales, UK.

Clinical Studies & Research Consultant, Perpet Production, Kolumbusstr. 29, 70439, Stuttgart, Germany.

出版信息

Crit Care. 2017 Mar 14;21(1):52. doi: 10.1186/s13054-017-1635-z.

Abstract

BACKGROUND

Delayed response to clinical deterioration of ward patients is common.

METHODS

We performed a prospective before-and-after study in all patients admitted to two clinical ward areas in a district general hospital in the UK. We examined the effect on clinical outcomes of deploying an electronic automated advisory vital signs monitoring and notification system, which relayed abnormal vital signs to a rapid response team (RRT).

RESULTS

We studied 2139 patients before (control) and 2263 after the intervention. During the intervention the number of RRT notifications increased from 405 to 524 (p = 0.001) with more notifications triggering fluid therapy, bronchodilators and antibiotics. Moreover, despite an increase in the number of patients with "do not attempt resuscitation" orders (from 99 to 135; p = 0.047), mortality decreased from 173 to 147 (p = 0.042) patients and cardiac arrests decreased from 14 to 2 events (p = 0.002). Finally, the severity of illness in patients admitted to the ICU was reduced (mean Acute Physiology and Chronic Health Evaluation II score: 26 (SD 9) vs. 18 (SD 8)), as was their mortality (from 45% to 24%; p = 0.04).

CONCLUSIONS

Deployment of an electronic automated advisory vital signs monitoring and notification system to signal clinical deterioration in ward patients was associated with significant improvements in key patient-centered clinical outcomes.

TRIAL REGISTRATION

ClinicalTrials.gov, NCT01692847 . Registered on 21 September 2012.

摘要

背景

病房患者临床恶化时的延迟反应较为常见。

方法

我们在英国一家地区综合医院的两个临床病房进行了一项前瞻性的前后对照研究。我们研究了部署电子自动生命体征监测和通知系统对临床结果的影响,该系统将异常生命体征转发给快速反应小组(RRT)。

结果

我们研究了干预前(对照组)的 2139 例患者和干预后的 2263 例患者。干预期间,RRT 通知的数量从 405 例增加到 524 例(p=0.001),更多的通知触发了液体疗法、支气管扩张剂和抗生素的应用。此外,尽管“不尝试复苏”医嘱的患者数量从 99 例增加到 135 例(p=0.047),但死亡率从 173 例下降到 147 例(p=0.042),心搏骤停从 14 例下降到 2 例(p=0.002)。最后,入住 ICU 的患者的疾病严重程度降低(平均急性生理学和慢性健康评估 II 评分:26(9 分)vs. 18(8 分)),死亡率也降低(从 45%降至 24%;p=0.04)。

结论

部署电子自动生命体征监测和通知系统以提示病房患者的临床恶化与关键以患者为中心的临床结果的显著改善相关。

试验注册

ClinicalTrials.gov,NCT01692847。于 2012 年 9 月 21 日注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b98/5348741/99f856674fff/13054_2017_1635_Fig1_HTML.jpg

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