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本文引用的文献

1
Soft Lithography.软光刻
Angew Chem Int Ed Engl. 1998 Mar 16;37(5):550-575. doi: 10.1002/(SICI)1521-3773(19980316)37:5<550::AID-ANIE550>3.0.CO;2-G.
2
Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers.奥斯特瓦尔德阶段律控制着二肽超分子聚合物的结构转变和形态。
Nat Commun. 2014 Nov 13;5:5219. doi: 10.1038/ncomms6219.
3
A portable, benchtop photolithography system based on a solid-state light source.一种基于固态光源的便携式台式光刻系统。
Small. 2011 Nov 18;7(22):3144-7. doi: 10.1002/smll.201101209. Epub 2011 Sep 8.
4
Observation of spatial propagation of amyloid assembly from single nuclei.从单个细胞核观察淀粉样蛋白组装的空间传播。
Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14746-51. doi: 10.1073/pnas.1105555108. Epub 2011 Aug 26.
5
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane).聚二甲基硅氧烷微流控系统的快速成型
Anal Chem. 1998 Dec 1;70(23):4974-84. doi: 10.1021/ac980656z.
6
Maskless photolithography using UV LEDs.使用紫外发光二极管的无掩膜光刻技术。
Lab Chip. 2008 Aug;8(8):1402-4. doi: 10.1039/b800465j. Epub 2008 Jun 23.
7
Drop-based microfluidic devices for encapsulation of single cells.用于单细胞封装的液滴微流控装置。
Lab Chip. 2008 Jul;8(7):1110-5. doi: 10.1039/b802941e. Epub 2008 May 23.

采用快速晶圆级LED光刻图案化技术制造的微流控器件。

Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.

作者信息

Challa Pavan K, Kartanas Tadas, Charmet Jérôme, Knowles Tuomas P J

机构信息

Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge CB2 1EW, United Kingdom.

出版信息

Biomicrofluidics. 2017 Feb 17;11(1):014113. doi: 10.1063/1.4976690. eCollection 2017 Jan.

DOI:10.1063/1.4976690
PMID:28289484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5315664/
Abstract

Current lithography approaches underpinning the fabrication of microfluidic devices rely on UV exposure of photoresists to define microstructures in these materials. Conventionally, this objective is achieved with gas discharge mercury lamps, which are capable of producing high intensity UV radiation. However, these sources are costly, have a comparatively short lifetime, necessitate regular calibration, and require significant time to warm up prior to exposure taking place. To address these limitations we exploit advances in solid state sources in the UV range and describe a fast and robust wafer-scale laboratory exposure system relying entirely on UV-Light emitting diode (UV-LED) illumination. As an illustration of the potential of this system for fast and low-cost microfluidic device production, we demonstrate the microfabrication of a 3D spray-drying microfluidic device and a 3D double junction microdroplet maker device.

摘要

当前用于制造微流控器件的光刻方法依赖于对光刻胶进行紫外线曝光,以在这些材料中定义微结构。传统上,这一目标是通过气体放电汞灯实现的,汞灯能够产生高强度紫外线辐射。然而,这些光源成本高昂,使用寿命相对较短,需要定期校准,并且在曝光前需要大量时间预热。为了解决这些限制,我们利用了紫外波段固态光源的进展,并描述了一种完全依赖紫外发光二极管(UV-LED)照明的快速且稳健的晶圆级实验室曝光系统。作为该系统在快速和低成本微流控器件生产方面潜力的一个例证,我们展示了一种3D喷雾干燥微流控器件和一种3D双结微滴制造器件的微制造过程。