Stoffel Joseph, Bernatchez Stéphanie F
3M Critical & Chronic Care Solutions Division , St. Paul, Minnesota.
3M Health Care Clinical Operations , St. Paul, Minnesota.
Adv Wound Care (New Rochelle). 2017 Mar 1;6(3):73-79. doi: 10.1089/wound.2016.0706.
Evaluate the effect of a new investigational skin protectant formulation on the growth of various microorganisms . An laboratory assay with various species of gram-positive bacteria, gram-negative bacteria, and yeast grown on agar plates was used to verify that a new investigational product used for the management of incontinence-associated dermatitis (IAD) does not support microbial growth. The investigational product did not support the growth of all organisms tested for 48 h in these assays. The results demonstrate the barrier properties of this investigational formulation against bacteria and yeast that are relevant to incontinent patients. IAD accompanied by skin damage is difficult to manage with currently available products. A new skin protectant that can be applied as a liquid and polymerizes into a breathable film even in the presence of exudate (as shown previously) has been developed and tested to ensure that it does not support microbial growth. This work verifies that this new product does not support microbial growth using organisms relevant for the intended application.
评估一种新型试验性皮肤保护剂配方对各种微生物生长的影响。采用在琼脂平板上培养多种革兰氏阳性菌、革兰氏阴性菌和酵母菌的实验室检测方法，以验证一种用于治疗失禁相关性皮炎（IAD）的新型试验性产品是否不支持微生物生长。在这些检测中，该试验性产品在48小时内不支持所有受试微生物的生长。结果表明，这种试验性配方对与失禁患者相关的细菌和酵母菌具有屏障特性。伴有皮肤损伤的IAD目前难以用现有产品进行处理。一种新型皮肤保护剂已被开发并测试，它可以作为液体涂抹，并能在有渗出液的情况下（如之前所示）聚合成透气膜，以确保它不支持微生物生长。这项工作使用与预期应用相关的微生物验证了这种新产品不支持微生物生长。
