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Genome-wide in vivo screen identifies host molecule in promoting cancer metastasis.

作者信息

Gu Yan, Liu Yanfang, Cao Xuetao

机构信息

National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.

Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, China.

出版信息

Protein Cell. 2017 Jun;8(6):398-400. doi: 10.1007/s13238-017-0391-9.

DOI:10.1007/s13238-017-0391-9
PMID:28290052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5445027/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/284e/5445027/c8649a2330e4/13238_2017_391_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/284e/5445027/c8649a2330e4/13238_2017_391_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/284e/5445027/c8649a2330e4/13238_2017_391_Fig1_HTML.jpg

相似文献

1
Genome-wide in vivo screen identifies host molecule in promoting cancer metastasis.全基因组体内筛选鉴定出促进癌症转移的宿主分子。
Protein Cell. 2017 Jun;8(6):398-400. doi: 10.1007/s13238-017-0391-9.
2
Mutant mitochondria and cancer cell metastasis: quest for a mechanism.突变线粒体与癌细胞转移：探寻一种机制
Cancer Biol Ther. 2009 Jul;8(14):1386-8. doi: 10.4161/cbt.8.14.9030.
3
[The role of glycosphingolipids in the expression of neoplastic phenotype. III. Changes in glycosphingolipids related to the capacity of neoplastic cells for metastasis and tumor growth in vivo].[糖鞘脂在肿瘤表型表达中的作用。III. 与肿瘤细胞体内转移能力和肿瘤生长相关的糖鞘脂变化]
Postepy Hig Med Dosw. 1992;46(2):191-208.
4
Tumor heterogeneity in metastasis.转移中的肿瘤异质性。
Prog Clin Biol Res. 1986;212:45-59.
5
Recent work adds support to theory that cells may have metastatic origin.近期的研究为细胞可能具有转移起源这一理论提供了支持。
J Natl Cancer Inst. 2004 Sep 1;96(17):1272-3. doi: 10.1093/jnci/96.17.1272.
6
Drosophila as an emerging model to study metastasis.果蝇作为一种新兴的转移研究模型。
Genome Biol. 2004;5(4):216. doi: 10.1186/gb-2004-5-4-216. Epub 2004 Mar 25.
7
CMAP: a novel cystatin-like gene involved in liver metastasis.
Cancer Res. 1999 Jan 1;59(1):151-8.
8
Relevance of spontaneous in vivo tumor-host cell fusion to tumor progression and metastasis evaluated using a series of lectin-resistant mutant tumor sublines.利用一系列凝集素抗性突变肿瘤亚系评估体内自发肿瘤-宿主细胞融合与肿瘤进展和转移的相关性。
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本文引用的文献

1
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization.全基因组体内筛选鉴定出转移定植的新型宿主调节因子。
Nature. 2017 Jan 12;541(7636):233-236. doi: 10.1038/nature20792. Epub 2017 Jan 4.
2
Characteristics and Significance of the Pre-metastatic Niche.前转移龛的特征和意义。
Cancer Cell. 2016 Nov 14;30(5):668-681. doi: 10.1016/j.ccell.2016.09.011.
3
Crystal clear: visualizing the intervention mechanism of the PD-1/PD-L1 interaction by two cancer therapeutic monoclonal antibodies.一清二楚：通过两种癌症治疗性单克隆抗体可视化PD-1/PD-L1相互作用的干预机制。
Protein Cell. 2016 Dec;7(12):866-877. doi: 10.1007/s13238-016-0337-7. Epub 2016 Nov 4.
4
Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils.肿瘤细胞外泌体 RNA 通过激活肺泡上皮 TLR3 招募中性粒细胞促进肺转移前龛形成。
Cancer Cell. 2016 Aug 8;30(2):243-256. doi: 10.1016/j.ccell.2016.06.021.
5
T cell exclusion, immune privilege, and the tumor microenvironment.T 细胞排斥、免疫特权和肿瘤微环境。
Science. 2015 Apr 3;348(6230):74-80. doi: 10.1126/science.aaa6204.
6
Tackling the tumor microenvironment: what challenge does it pose to anticancer therapies?应对肿瘤微环境：它给抗癌治疗带来了哪些挑战？
Protein Cell. 2014 Nov;5(11):816-26. doi: 10.1007/s13238-014-0097-1. Epub 2014 Sep 5.
7
Microenvironmental regulation of tumor progression and metastasis.肿瘤演进和转移的微环境调控。
Nat Med. 2013 Nov;19(11):1423-37. doi: 10.1038/nm.3394.
8
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.全基因组敲除小鼠的生成和系统表型分析揭示了许多基因的新作用。
Cell. 2013 Jul 18;154(2):452-64. doi: 10.1016/j.cell.2013.06.022.
9
The blockade of immune checkpoints in cancer immunotherapy.癌症免疫疗法中的免疫检查点阻断。
Nat Rev Cancer. 2012 Mar 22;12(4):252-64. doi: 10.1038/nrc3239.
10
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1.淋巴细胞从胸腺和外周淋巴器官的输出依赖于S1P受体1。
Nature. 2004 Jan 22;427(6972):355-60. doi: 10.1038/nature02284.