Sizova Zh M, Zakharova V L, Kozlova N V, Kuchkina T S
Sechenov First Moscow State Medical University, Moscow, Russia.
Central Clinical Hospital with Polyclinic President Management Department RF, Moscow, Russia.
Kardiologiia. 2016 Jun;56(6):26-31. doi: 10.18565/cardio.2016.6.26-31.
The aim of the study to assess the influence of medicamentous therapy to the quality of life of ischemic heart disease patients with stable angina pectoris by activator potassium channels nicorandil in comparison with traditional therapy by isosorbide dinitrate. The study included 84 ischemic heart disease patients. Authors consider quality of life as an estimated category of state of the subject in an illness situation. The dynamic of physical and psychological components of quality of life are compared in ischemic heart disease patients under the treatment by nicorandil and isosorbide dinitrate. Indicators of quality of life, defined on the basis of a questionnaires of SAQ and GHQ supplementing an illness picture, are an multiple-factor criterion of an assessment of a condition of this category of patients. The benefits of nicorandil in influence on quality of life indicators were revealed in the study.
本研究旨在评估与传统药物硝酸异山梨酯治疗相比，钾通道激活剂尼可地尔药物治疗对稳定型心绞痛缺血性心脏病患者生活质量的影响。该研究纳入了84例缺血性心脏病患者。作者将生活质量视为疾病状态下受试者状况的一个评估类别。比较了尼可地尔和硝酸异山梨酯治疗的缺血性心脏病患者生活质量的生理和心理成分动态变化。基于补充病情描述的SAQ问卷和GHQ问卷定义的生活质量指标，是评估这类患者病情的多因素标准。该研究揭示了尼可地尔对生活质量指标影响的益处。
