Harrold Leslie R, Etzel Carol J, Gibofsky Allan, Kremer Joel M, Pillinger Michael H, Saag Kenneth G, Schlesinger Naomi, Terkeltaub Robert, Cox Vanessa, Greenberg Jeffrey D
Department of Medicine and Orthopedics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA.
Corrona, LLC, Southborough, MA, USA.
BMC Musculoskelet Disord. 2017 Mar 14;18(1):108. doi: 10.1186/s12891-017-1465-9.
To characterize the differences between women and men with gout.
We analyzed a US national cohort of gout patients cared for by rheumatologists.
Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).
The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.
描述痛风女性患者和男性患者之间的差异。
我们分析了美国一个由风湿病学家诊治的痛风患者全国队列。
与1012名痛风男性患者相比，痛风女性患者（n = 262）年龄更大（71岁对61岁，p < 0.001），合并症负担更重（高血压、糖尿病、肾病和肥胖的p < 0.001）。痛风的危险因素有所不同，女性更常服用利尿剂（p < 0.001），而男性饮食诱发因素更常见（p < 0.05）。
痛风女性患者和男性患者的情况明显不同，提示需要调整治疗建议。
