痛风特征的性别差异：针对女性和男性的个性化护理
Sex differences in gout characteristics: tailoring care for women and men.
作者信息
Harrold Leslie R, Etzel Carol J, Gibofsky Allan, Kremer Joel M, Pillinger Michael H, Saag Kenneth G, Schlesinger Naomi, Terkeltaub Robert, Cox Vanessa, Greenberg Jeffrey D
机构信息
Department of Medicine and Orthopedics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA.
Corrona, LLC, Southborough, MA, USA.
出版信息
BMC Musculoskelet Disord. 2017 Mar 14;18(1):108. doi: 10.1186/s12891-017-1465-9.
BACKGROUND
To characterize the differences between women and men with gout.
METHODS
We analyzed a US national cohort of gout patients cared for by rheumatologists.
RESULTS
Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).
CONCLUSIONS
The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.
背景
描述痛风女性患者和男性患者之间的差异。
方法
我们分析了美国一个由风湿病学家诊治的痛风患者全国队列。
结果
与1012名痛风男性患者相比，痛风女性患者（n = 262）年龄更大（71岁对61岁，p < 0.001），合并症负担更重（高血压、糖尿病、肾病和肥胖的p < 0.001）。痛风的危险因素有所不同，女性更常服用利尿剂（p < 0.001），而男性饮食诱发因素更常见（p < 0.05）。
结论
痛风女性患者和男性患者的情况明显不同，提示需要调整治疗建议。
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