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胚胎移植模拟可提高妊娠率,并缩短生殖内分泌与不孕症专科培训医师进行胚胎移植达到熟练程度所需的时间。

Embryo transfer simulation improves pregnancy rates and decreases time to proficiency in Reproductive Endocrinology and Infertility fellow embryo transfers.

作者信息

Heitmann Ryan J, Hill Micah J, Csokmay John M, Pilgrim Justin, DeCherney Alan H, Deering Shad

机构信息

Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, Washington.

Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland.

出版信息

Fertil Steril. 2017 May;107(5):1166-1172.e1. doi: 10.1016/j.fertnstert.2017.01.016. Epub 2017 Mar 11.

Abstract

OBJECTIVE

To design and evaluate an ET simulator to train Reproductive Endocrinology and Infertility (REI) fellows' techniques of ET.

DESIGN

Simulation model development and retrospective cohort analysis.

SETTING

Not applicable.

PATIENT(S): Patients undergoing IVF.

INTERVENTION(S): Simulation model evaluation and implementation of ET simulation training.

MAIN OUTCOME MEASURE(S): Pregnancy rates.

RESULT(S): The REI fellow and faculty evaluation responses (n = 19/21 [90%]) of the model demonstrated realistic characteristics, with evaluators concluding the model was suitable for training in almost all evaluated areas. A total of 12 REI fellows who performed ET were analyzed: 6 before ET trainer and 6 after ET trainer. Pregnancy rates were 31% in the initial 10 ETs per fellow before simulator vs. 46% after simulator. One of six pre-ET trainer fellows (17%) had pregnancy rates ≥40% in their first 10 ETs; whereas four of six post-ET trainer fellows had pregnancy rates ≥40% in their first 10 ETs. The average number of ETs to obtain >40% pregnancy efficiency was 27 ETs before trainer vs. 15 ETs after trainer. Pregnancy rates were similar in the two groups after 20 ETs, and collective terminal pregnancy rates were >50% after 40 ETs.

CONCLUSION(S): Embryo transfer simulation improved REI fellow pregnancy rates in their first 10 transfers and led to a more rapid ET proficiency. These data suggest potential value in adopting ET simulation, even in programs with a robust history of live ET in fellowship training.

摘要

目的

设计并评估一种胚胎移植(ET)模拟器,以培训生殖内分泌与不孕症(REI)专科住院医师的ET技术。

设计

模拟模型开发及回顾性队列分析。

地点

不适用。

患者

接受体外受精(IVF)的患者。

干预措施

模拟模型评估及ET模拟培训的实施。

主要观察指标

妊娠率。

结果

19/21(90%)的REI专科住院医师和教员对该模型的评估反馈显示其具有逼真的特性,评估者认为该模型几乎在所有评估领域都适合用于培训。对总共12名进行ET的REI专科住院医师进行了分析:6名在使用ET训练器之前,6名在使用ET训练器之后。每位专科住院医师在模拟器使用前最初的10次ET中的妊娠率为31%,使用模拟器后为46%。6名ET训练器使用前的专科住院医师中有1名(17%)在其最初的10次ET中的妊娠率≥40%;而6名ET训练器使用后的专科住院医师中有4名在其最初的10次ET中的妊娠率≥40%。在训练器使用前,获得>40%妊娠效率的平均ET次数为27次,使用训练器后为15次。20次ET后两组的妊娠率相似,40次ET后总体最终妊娠率>50%。

结论

胚胎移植模拟提高了REI专科住院医师最初10次移植的妊娠率,并使其更快地掌握ET技术。这些数据表明,即使在专科培训中有丰富的活体ET历史的项目中,采用ET模拟也具有潜在价值。

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