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汇聚类器官领域:从早期起源到未来之路。

Bringing together the organoid field: from early beginnings to the road ahead.

作者信息

Muthuswamy Senthil K

机构信息

Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA

出版信息

Development. 2017 Mar 15;144(6):963-967. doi: 10.1242/dev.144444.

Abstract

From October 12-15th, 2016, EMBO∣EMBL held a symposium to bring together those in the scientific community with a shared interest in using three-dimensional (3D) culture methods to study biology, model disease and personalize treatments. The symposium, entitled 'Organoids: modelling organ development and disease in 3D culture', which was organized by Juergen Knoblich, Mina Bissell and Esther Schnapp, was particularly timely as there were otherwise few opportunities for those interested in using 3D culture platforms to interact outside of their organ-specific scientific community. The meeting was a fantastic success, creating a lot of discussion and cross-fertilization of ideas from developmental biologists to bioengineers and biophysicists. This Meeting Review provides a summary of the talks presented and the major themes that emerged from the symposium.

摘要

2016年10月12日至15日,欧洲分子生物学组织(EMBO)与欧洲分子生物学实验室(EMBL)联合举办了一场研讨会,旨在汇聚科学界中对运用三维(3D)培养方法来研究生物学、模拟疾病及实现个性化治疗有着共同兴趣的人士。这场名为“类器官:在3D培养中模拟器官发育与疾病”的研讨会由于尔根·克诺布利希、米娜·比塞尔和埃丝特·施纳普组织。此次研讨会尤为及时,因为对于那些有兴趣使用3D培养平台的人来说,在其特定器官的科学界之外,相互交流的机会很少。会议取得了巨大成功,引发了众多讨论,并促进了从发育生物学家到生物工程师和生物物理学家等不同领域间的思想交叉融合。本会议综述总结了会上的发言内容以及研讨会中出现的主要主题。

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