• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A型肉毒毒素在亚洲人的美学应用:一项国际、多学科、泛亚共识。

Aesthetic Applications of Botulinum Toxin A in Asians: An International, Multidisciplinary, Pan-Asian Consensus.

作者信息

Sundaram Hema, Huang Po-Han, Hsu Nai-Jen, Huh Chang Hun, Wu Woffles T L, Wu Yan, Cassuto Daniel, Kerscher Martina J, Seo Kyle Koo-Il

机构信息

Dermatology, Cosmetic & Laser Surgery, Rockville, Md.; Huang PH Dermatology and Aesthetics, Kaohsiung, Taiwan; and Aesthetics Center, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan; Dermatological Clinic, Tainan, Taiwan; Seoul National University Bundang Hospital, Seoul, South Korea; Aesthetic Surgery and Laser Centre, Singapore, Singapore; Peking University First Hospital, Beijing, China; University of Modena, Modena, Italy; Division of Cosmetic Sciences, University of Hamburg, Hamburg, Germany; and Seoul National University Hospital, Seoul, South Korea.

出版信息

Plast Reconstr Surg Glob Open. 2016 Dec 7;4(12):e872. doi: 10.1097/GOX.0000000000000507. eCollection 2016 Dec.

DOI:10.1097/GOX.0000000000000507
PMID:28293488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5222633/
Abstract

BACKGROUND

Botulinum toxin type A remains the most popular nonsurgical aesthetic treatment worldwide. Previous consensus statements have focused on Caucasians and on Koreans as generally representative of Asians. However, indications and dosages vary among different ethnic groups. This publication reports the results of a multidisciplinary, pan-Asian consensus focusing on incobotulinumtoxinA.

METHODS

A consensus group of plastic surgeons and dermatologists from Asia, Europe, and the United States convened for a live meeting in Asia, followed by a questionnaire-based Delphi procedure. Treatment of Asians in both their native countries and countries of migration was discussed.

RESULTS

For most items, the group achieved a majority consensus. A number of treatment indications, strategies, and dosages were identified in Asians, which are distinct to those previously described for Caucasians due to differences in facial morphotypes, anatomy, and cultural expectations. The group also formulated position statements for intradermal botulinum toxin type A ("mesotoxin"), body shaping with the calves as a paradigm, and reduction of parotid glands. While Asians have previously been considered a homogeneous group for the purposes of aesthetic treatment, this publication considers regional variations. A new classification of Asian facial morphotypes is proposed to aid treatment planning and implementation.

CONCLUSIONS

This is the first pan-Asian consensus for aesthetic use of botulinum toxin type A. Its unique objective is to optimize treatment safety and efficacy for patients of complete or part-Asian ancestry in all regions. The recommendations for incobotulinumtoxinA may be extended with care to other botulinum toxin formulations.

摘要

背景

A型肉毒毒素仍然是全球最受欢迎的非手术美容治疗方法。以往的共识声明主要关注白种人以及通常作为亚洲人代表的韩国人。然而,不同种族群体的适应症和剂量有所不同。本出版物报告了一项针对注射用A型肉毒毒素的多学科泛亚共识的结果。

方法

来自亚洲、欧洲和美国的整形外科医生和皮肤科医生组成的共识小组在亚洲召开了一次现场会议,随后进行了基于问卷的德尔菲法程序。讨论了在亚洲人本国以及移民国家对他们的治疗。

结果

对于大多数项目,该小组达成了多数共识。在亚洲人中确定了一些治疗适应症、策略和剂量,由于面部形态、解剖结构和文化期望的差异,这些与先前对白种人描述的不同。该小组还制定了关于皮内注射A型肉毒毒素(“微毒素”)、以小腿塑形为例的身体塑形以及腮腺缩小的立场声明。虽然以前在美容治疗方面亚洲人被视为一个同质群体,但本出版物考虑了区域差异。提出了一种新的亚洲面部形态分类,以帮助治疗计划的制定和实施。

结论

这是第一项关于A型肉毒毒素美容用途的泛亚共识。其独特目标是优化所有地区完全或部分亚洲血统患者的治疗安全性和有效性。注射用A型肉毒毒素的建议可能需要谨慎地扩展到其他肉毒毒素制剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a413/5222633/bd04bf99da9f/gox-4-0e872-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a413/5222633/36271e1f6355/gox-4-0e872-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a413/5222633/bd04bf99da9f/gox-4-0e872-g019.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a413/5222633/36271e1f6355/gox-4-0e872-g018.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a413/5222633/bd04bf99da9f/gox-4-0e872-g019.jpg

相似文献

1
Aesthetic Applications of Botulinum Toxin A in Asians: An International, Multidisciplinary, Pan-Asian Consensus.A型肉毒毒素在亚洲人的美学应用:一项国际、多学科、泛亚共识。
Plast Reconstr Surg Glob Open. 2016 Dec 7;4(12):e872. doi: 10.1097/GOX.0000000000000507. eCollection 2016 Dec.
2
Use of LetibotulinumtoxinA for Aesthetic Treatment of Asians: A Consensus.《用于亚洲人美学治疗的乐提葆肉毒素共识》
Aesthet Surg J. 2023 Oct 13;43(11):NP962-NP974. doi: 10.1093/asj/sjad151.
3
Consensus on Changing Trends, Attitudes, and Concepts of Asian Beauty.亚洲之美:审美潮流、观念、态度的转变。
Aesthetic Plast Surg. 2020 Aug;44(4):1186-1194. doi: 10.1007/s00266-020-01808-w. Epub 2015 Sep 25.
4
Consensus Statement on the Use of Botulinum Neurotoxin in the Middle East.中东地区肉毒杆菌神经毒素使用共识声明
Clin Cosmet Investig Dermatol. 2023 Oct 17;16:2899-2909. doi: 10.2147/CCID.S420921. eCollection 2023.
5
The convergence of medicine and neurotoxins: a focus on botulinum toxin type A and its application in aesthetic medicine--a global, evidence-based botulinum toxin consensus education initiative: part I: botulinum toxin in clinical and cosmetic practice.医学与神经毒素的融合:聚焦 A 型肉毒毒素及其在美容医学中的应用——一项基于全球证据的肉毒毒素共识教育计划:第一部分:肉毒毒素在临床和美容实践中的应用。
Dermatol Surg. 2013 Mar;39(3 Pt 2):493-509. doi: 10.1111/dsu.12147.
6
IncobotulinumtoxinA in aesthetics: Russian multidisciplinary expert consensus recommendations.美学领域中的A型肉毒杆菌毒素:俄罗斯多学科专家共识建议
Clin Cosmet Investig Dermatol. 2015 Jun 5;8:297-306. doi: 10.2147/CCID.S72301. eCollection 2015.
7
Italian consensus report on the aesthetic use of onabotulinum toxin A.意大利关于A型肉毒毒素美学用途的共识报告。
J Cosmet Dermatol. 2018 Oct;17(5):719-730. doi: 10.1111/jocd.12729. Epub 2018 Aug 9.
8
The convergence of medicine and neurotoxins: a focus on botulinum toxin type A and its application in aesthetic medicine--a global, evidence-based botulinum toxin consensus education initiative: part II: incorporating botulinum toxin into aesthetic clinical practice.医学与神经毒素的融合:以 A 型肉毒毒素为重点及其在美容医学中的应用——一项全球性、基于证据的肉毒毒素共识教育计划:第二部分:将肉毒毒素纳入美容临床实践。
Dermatol Surg. 2013 Mar;39(3 Pt 2):510-25. doi: 10.1111/dsu.12148.
9
PAN-ASIAN CONSENSUS-Key Recommendations for Adapting the World Congress of Dermatology Consensus on Combination Treatment with Injectable Fillers, Toxins, and Ultrasound Devices in Asian Patients.泛亚共识——关于调整世界皮肤科大会在亚洲患者中联合使用注射填充剂、毒素和超声设备的共识的关键建议。
J Clin Aesthet Dermatol. 2017 Aug;10(8):16-27. Epub 2017 Aug 1.
10
Tailored botulinum toxin type A injections in aesthetic medicine: consensus panel recommendations for treating the forehead based on individual facial anatomy and muscle tone.美容医学中A型肉毒杆菌毒素的定制注射:基于个体面部解剖结构和肌肉张力治疗前额的共识小组建议。
Clin Cosmet Investig Dermatol. 2017 Oct 19;10:413-421. doi: 10.2147/CCID.S138274. eCollection 2017.

引用本文的文献

1
Personality Traits and Motivations of Chinese Adults Seeking Cosmetic Botulinum Toxin Injection.寻求肉毒杆菌毒素注射美容的中国成年人的人格特质与动机
Clin Cosmet Investig Dermatol. 2025 Mar 25;18:709-719. doi: 10.2147/CCID.S511665. eCollection 2025.
2
An Anthropometric Study of the Morphologic Facial Index of Tibetan Youth in Tibet.西藏藏族青少年面形态指数的人体测量学研究。
J Craniofac Surg. 2024;35(2):490-494. doi: 10.1097/SCS.0000000000009766. Epub 2023 Oct 17.
3
An Ultrasonographic Analysis of the Deep Inferior Tendon in the Masseter Muscle: Implications for Botulinum Toxin Injections.

本文引用的文献

1
Global Aesthetics Consensus: Botulinum Toxin Type A--Evidence-Based Review, Emerging Concepts, and Consensus Recommendations for Aesthetic Use, Including Updates on Complications.全球美学共识:A型肉毒毒素——基于证据的综述、新概念以及美学应用的共识性建议,包括并发症的最新情况
Plast Reconstr Surg. 2016 Mar;137(3):518e-529e. doi: 10.1097/01.prs.0000475758.63709.23.
2
Clinical equivalence of conventional OnabotulinumtoxinA (900 KDa) and IncobotulinumtoxinA (neurotoxin free from complexing proteins - 150 KDa): 2012 multidisciplinary French consensus in aesthetics.传统的A型肉毒杆菌毒素(900千道尔顿)与因可肉毒素A(不含复合蛋白的神经毒素 - 150千道尔顿)的临床等效性:2012年法国美学多学科共识
J Drugs Dermatol. 2013 Dec;12(12):1434-46.
3
咀嚼肌深部下颌骨肌腱的超声分析:肉毒毒素注射的意义。
Toxins (Basel). 2024 Sep 11;16(9):391. doi: 10.3390/toxins16090391.
4
Botulinum toxin treatment for hemifacial spasm: harmonising neurological and aesthetic outcomes.肉毒杆菌毒素治疗面肌痉挛:协调神经学和美学效果。
J Neural Transm (Vienna). 2025 Jan;132(1):23-38. doi: 10.1007/s00702-024-02821-y. Epub 2024 Aug 23.
5
Clinical Tips for Non-Invasive Cosmetic Procedures in Skin of Color Patients.有色人种患者非侵入性美容手术的临床小贴士
J Clin Aesthet Dermatol. 2024 Mar;17(3-4 Suppl 1):S24-S25.
6
Aesthetic doctors' perception and attitudes toward tolerance in botulinum toxin.美学医生对肉毒毒素耐受性的认知和态度。
Skin Res Technol. 2024 Apr;30(4):e413691. doi: 10.1111/srt.13691.
7
Consensus Statement on the Use of Botulinum Neurotoxin in the Middle East.中东地区肉毒杆菌神经毒素使用共识声明
Clin Cosmet Investig Dermatol. 2023 Oct 17;16:2899-2909. doi: 10.2147/CCID.S420921. eCollection 2023.
8
Addressing the Real-World Challenges of Immunoresistance to Botulinum Neurotoxin A in Aesthetic Practice: Insights and Recommendations from a Panel Discussion in Hong Kong.解决美容实践中肉毒毒素 A 免疫抵抗的现实挑战:来自香港小组讨论的见解和建议。
Toxins (Basel). 2023 Jul 12;15(7):456. doi: 10.3390/toxins15070456.
9
Use of LetibotulinumtoxinA for Aesthetic Treatment of Asians: A Consensus.《用于亚洲人美学治疗的乐提葆肉毒素共识》
Aesthet Surg J. 2023 Oct 13;43(11):NP962-NP974. doi: 10.1093/asj/sjad151.
10
Botulinum Toxin Type A for the Treatment of Masseter Muscle Prominence in Asian Populations.A型肉毒杆菌毒素治疗亚洲人群咬肌突出症
Aesthet Surg J Open Forum. 2023 Feb 7;5:ojad005. doi: 10.1093/asjof/ojad005. eCollection 2023.
Consensus recommendations on the aesthetic usage of botulinum toxin type A in Asians.
关于 A 型肉毒毒素在亚洲人群中的美容应用的共识建议。
Dermatol Surg. 2013 Dec;39(12):1843-60. doi: 10.1111/dsu.12317. Epub 2013 Oct 11.
4
Anatomical study of the corrugator supercilii muscle and its clinical implication with botulinum toxin A injection.皱眉肌的解剖学研究及其与A型肉毒毒素注射的临床关联
Surg Radiol Anat. 2013 Nov;35(9):817-21. doi: 10.1007/s00276-013-1174-5. Epub 2013 Jul 30.
5
Regulation of lipid production by acetylcholine signalling in human sebaceous glands.乙酰胆碱信号在人体皮脂腺脂质生成中的调节作用。
J Dermatol Sci. 2013 Nov;72(2):116-22. doi: 10.1016/j.jdermsci.2013.06.009. Epub 2013 Jun 28.
6
Botulinum toxin injection for salivary gland enlargement evaluated using computed tomographic volumetry.使用计算机断层扫描体积测量法评估肉毒杆菌毒素注射治疗唾液腺肿大的效果。
Dermatol Surg. 2013 Sep;39(9):1404-7. doi: 10.1111/dsu.12247. Epub 2013 Jul 1.
7
The convergence of medicine and neurotoxins: a focus on botulinum toxin type A and its application in aesthetic medicine--a global, evidence-based botulinum toxin consensus education initiative: part II: incorporating botulinum toxin into aesthetic clinical practice.医学与神经毒素的融合:以 A 型肉毒毒素为重点及其在美容医学中的应用——一项全球性、基于证据的肉毒毒素共识教育计划:第二部分:将肉毒毒素纳入美容临床实践。
Dermatol Surg. 2013 Mar;39(3 Pt 2):510-25. doi: 10.1111/dsu.12148.
8
The convergence of medicine and neurotoxins: a focus on botulinum toxin type A and its application in aesthetic medicine--a global, evidence-based botulinum toxin consensus education initiative: part I: botulinum toxin in clinical and cosmetic practice.医学与神经毒素的融合:聚焦 A 型肉毒毒素及其在美容医学中的应用——一项基于全球证据的肉毒毒素共识教育计划:第一部分:肉毒毒素在临床和美容实践中的应用。
Dermatol Surg. 2013 Mar;39(3 Pt 2):493-509. doi: 10.1111/dsu.12147.
9
Safety and efficacy of intradermal injection of botulinum toxin for the treatment of oily skin.皮内注射肉毒毒素治疗油性皮肤的安全性和有效性。
Dermatol Surg. 2013 Mar;39(3 Pt 1):443-8. doi: 10.1111/dsu.12097. Epub 2013 Jan 7.
10
Nonsurgical rejuvenation of the upper eyelid and brow.上眼睑和眉部的非手术年轻化。
Clin Plast Surg. 2013 Jan;40(1):55-76. doi: 10.1016/j.cps.2012.08.009.