Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively.
作者信息
Long G L, Marshall A, Gardner J C, Naylor S L
机构信息
Department of Biochemistry, College of Medicine, University of Vermont, Burlington 05405.
出版信息
Somat Cell Mol Genet. 1988 Jan;14(1):93-8. doi: 10.1007/BF01535052.
PMID:2829367
Abstract
cDNAs encoding human proteins C and S have been used to screen a panel of mouse-human somatic cell hybrids to determine the chromosomal location of their respective genes. The gene for human protein C is located on chromosome 2, whereas that for protein S is located on chromosome 3. Analysis of human genomic DNA restriction endonuclease fragmentation patterns suggests that the human protein S gene is greater than 40 kb in size and contains a minimum of 11 introns.
摘要
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