物质使用障碍的非侵入性脑刺激结果：随机假对照临床试验综述
Outcome of Non-Invasive Brain Stimulation in Substance Use Disorders: A Review of Randomized Sham-Controlled Clinical Trials.
作者信息
Trojak Benoit, Sauvaget Anne, Fecteau Shirley, Lalanne Laurence, Chauvet-Gelinier Jean-Christophe, Koch Sonja, Bulteau Samuel, Zullino Daniele, Achab Sophia
机构信息
From the Department of Psychiatry and Addictology, University Hospital of Dijon, Dijon, France (BT, J-C C-G); the INSERM U1093, Cognition, Action et Plasticité Sensorimotrice, University of Burgundy-Franche-Comté, Dijon, France (BT); the CHU de Nantes, Psychiatric Neuromodulation Unit, Addictology and Liaison Psychiatry Department, Nantes, France (AS, SB); the Laboratory of Canada Research Chair in Cognitive Neuroplasticity, Centre Interdisciplinaire de Recherche en Réadaptation et Intégration Sociale, Centre de Recherche de l'Institut Universitaire en Santé Mentale de Quebec, Medical School, Laval University, Québec, Canada (SF); the Department of Psychiatry, University Hospital of Strasbourg, Strasbourg, France (LL); the Addiction Division, Department of Mental Health and Psychiatry, University Hospitals of Geneva, Switzerland (SA, DZ); and the Addictive Disorders Research Group and Neuroscience Center, University of Geneva, Switzerland (SA, DZ).
出版信息
J Neuropsychiatry Clin Neurosci. 2017 Spring;29(2):105-118. doi: 10.1176/appi.neuropsych.16080147. Epub 2017 Mar 15.
Non-invasive brain stimulation (NIBS) might be a new approach to treat substance use disorders (SUD). A systematic review and critical analysis was performed to identify potential therapeutic effects of NIBS on addictions. A search of the Medline database was conducted for randomized sham-controlled trials using NIBS in the field of addiction and published until August 2016. Twenty-six studies in various SUD met the inclusion criteria. Converging evidence indicates that NIBS might be a promising mean to treat patients with alcohol and tobacco use disorders, by acting on craving reduction and other mechanisms such as improvement in cognitive dysfunctions.
非侵入性脑刺激（NIBS）可能是治疗物质使用障碍（SUD）的一种新方法。进行了一项系统综述和批判性分析，以确定NIBS对成瘾的潜在治疗效果。在Medline数据库中搜索了截至2016年8月发表的、在成瘾领域使用NIBS的随机假对照试验。26项关于各种物质使用障碍的研究符合纳入标准。越来越多的证据表明，NIBS可能是治疗酒精和烟草使用障碍患者的一种有前景的手段，其作用机制包括减少渴望以及改善认知功能障碍等其他机制。
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