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808nm 激光激发的镧系掺杂纳米颗粒:合理设计、发光调控及诊疗应用。

808-nm-Light-Excited Lanthanide-Doped Nanoparticles: Rational Design, Luminescence Control and Theranostic Applications.

机构信息

State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.

University of the Chinese Academy of Sciences, Beijing, 100049, China.

出版信息

Adv Mater. 2017 May;29(18). doi: 10.1002/adma.201605434. Epub 2017 Mar 10.

DOI:10.1002/adma.201605434
PMID:28295673
Abstract

808 nm-light-excited lanthanide (Ln )-doped nanoparticles (LnNPs) hold great promise for a wide range of applications, including bioimaging diagnosis and anticancer therapy. This is due to their unique properties, including their minimized overheating effect, improved penetration depth, relatively high quantum yields, and other common features of LnNPs. In this review, the progress of 808 nm-excited LnNPs is reported, including their i) luminescence mechanism, ii) luminescence enhancement, iii) color tuning, iv) diagnostic and v) therapeutic applications. Finally, the future outlook and challenges of 808 nm-excited LnNPs are presented.

摘要

808nm 光激发的镧系(Ln)掺杂纳米粒子(LnNPs)在生物成像诊断和抗癌治疗等广泛应用中具有广阔的前景。这是由于它们具有独特的性质,包括最小化的过热效应、改善的穿透深度、相对较高的量子产率和 LnNPs 的其他常见特性。在这篇综述中,报告了 808nm 激发的 LnNPs 的进展,包括其 i)发光机制、ii)发光增强、iii)颜色调谐、iv)诊断和 v)治疗应用。最后,提出了 808nm 激发的 LnNPs 的未来展望和挑战。

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