Lee Young Bok, Kim Su Young, Park Yong Gyu, Han Kyung Do, Kim Jin-Wou, Chae Hiun Suk, Lee Young Chun
Department of Dermatology Department of Ophthalmology and Visual Science Department of Medical Statistics Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Medicine (Baltimore). 2017 Mar;96(11):e6343. doi: 10.1097/MD.0000000000006343.
Pterygium is a common conjunctival disorder. The socioeconomic risk factors of pterygium have not been systematically evaluated in Korea. The study investigated risk factors of pterygium considering socioeconomic status.Participants were 9839 adults aged 19 to 74 years, who underwent ophthalmic slit-lamp examinations as part of the Korean National Health and Nutrition Examination Survey 2010 to 2011. Pterygium was diagnosed as a growth of fibrovascular tissue over the cornea. The socioeconomic risk factors were analyzed in association with the presence of pterygium. Multiple logistic regression analysis was used to evaluate the odds ratios for differences in socioeconomic status.The presence of pterygium was associated with diabetes mellitus, hypertension, metabolic syndrome, and sun exposure time (>5 h/d). The blood level of 25-hydroxyvitamin D was higher in the pterygium group than in the control group, but both groups were deficient in 25-hydroxyvitamin D compared with the normal reference level. Pterygium was almost 3 times as frequent among persons who worked outdoors, such as skilled agricultural, forestry, and fishery workers, than among those who worked indoors (odds ratio 3.061, 95% confidence interval 1.946-4.813). Low educational status and longer working hours were also significantly associated with pterygium.This study used a nationwide population-based survey conducted by the Korean Centers for Disease Control and Prevention to reveal that pterygium is associated with low socioeconomic status. Efforts should be made to reduce the risk of pterygium by changing modifiable risk factors, especially among people with low socioeconomic status.
翼状胬肉是一种常见的结膜疾病。在韩国,尚未对翼状胬肉的社会经济风险因素进行系统评估。本研究在考虑社会经济地位的情况下调查了翼状胬肉的风险因素。
研究对象为9839名年龄在19至74岁之间的成年人,他们作为2010年至2011年韩国国家健康与营养检查调查的一部分接受了眼科裂隙灯检查。翼状胬肉被诊断为角膜上纤维血管组织的生长。分析了社会经济风险因素与翼状胬肉存在情况的相关性。采用多元逻辑回归分析来评估社会经济地位差异的比值比。
翼状胬肉的存在与糖尿病、高血压、代谢综合征以及阳光暴露时间(>5小时/天)相关。翼状胬肉组的25-羟基维生素D血水平高于对照组,但与正常参考水平相比,两组的25-羟基维生素D均缺乏。从事户外工作的人群,如熟练的农业、林业和渔业工人,患翼状胬肉的几率几乎是室内工作者的3倍(比值比3.061,95%置信区间1.946 - 4.813)。低教育水平和较长工作时间也与翼状胬肉显著相关。
本研究利用韩国疾病控制与预防中心进行的一项全国性基于人群的调查揭示,翼状胬肉与低社会经济地位相关。应努力通过改变可改变的风险因素来降低翼状胬肉的风险,特别是在社会经济地位较低的人群中。