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多能干细胞与生殖。

Multipotent Stem Cell and Reproduction.

作者信息

Khanlarkhani Neda, Baazm Maryam, Mohammadzadeh Farzaneh, Najafi Atefeh, Mehdinejadiani Shayesteh, Sobhani Aligholi

机构信息

Department of Anatomical Sciences, Medical School, Tehran University, Tehran, Iran.

Department of Anatomical Sciences, Medical School, Arak University, Arak, Iran.

出版信息

J Stem Cells. 2016;11(4):219-229.

Abstract

Stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. Stem cells can be classified into two main types based on their source of origin: Embryonic and Adult stem cells. Stem cells also classified based on the range of differentiation potentials into Totipotent, Pluripotent, Multipotent, and Unipotent. Multipotent stem cells have the ability to differentiate into all cell types within one particular lineage. There are plentiful advantages and usages for multipotent stem cells. Multipotent Stem cells act as a significant key in procedure of development, tissue repair, and protection. The accessibility and adaptability of these amazing cells create them a great therapeutic choice for different part of medical approaches, and it becomes interesting topic in the scientific researches to found obvious method for the most advantageous use of MSC-based therapies. Recent studies in the field of stem cell biology have provided new perspectives and opportunities for the treatment of infertility disorders.

摘要

干细胞是自我更新且未分化的细胞类型,能够分化为功能细胞。干细胞可根据其来源分为两种主要类型:胚胎干细胞和成体干细胞。干细胞还可根据分化潜能的范围分为全能、多能、多潜能和单能干细胞。多能干细胞有能力分化为一个特定谱系内的所有细胞类型。多能干细胞有诸多优势和用途。多能干细胞在发育、组织修复和保护过程中起着关键作用。这些神奇细胞的可获取性和适应性使其成为医学治疗不同领域的理想选择,并且如何找到基于间充质干细胞疗法的最有效使用方法也成为科学研究中的一个有趣课题。干细胞生物学领域的最新研究为不孕症的治疗提供了新的视角和机遇。

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