Sobhani Aligholi, Khanlarkhani Neda, Baazm Maryam, Mohammadzadeh Farzaneh, Najafi Atefeh, Mehdinejadiani Shayesteh, Sargolzaei Aval Fereydoon
Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Department of Anatomy, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Acta Med Iran. 2017 Jan;55(1):6-23.
Stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. Stem cells can be classified into two main types based on their source of origin: Embryonic and Adult stem cells. Stem cells also classified based on the range of differentiation potentials into Totipotent, Pluripotent, Multipotent, and Unipotent. Multipotent stem cells have the ability to differentiate into all cell types within one particular lineage. There are plentiful advantages and usages for multipotent stem cells. Multipotent Stem cells act as a significant key in procedure of development, tissue repair, and protection. Multipotent Stem cells have been applying in treatment of different disorders such as spinal cord injury, bone fracture, autoimmune diseases, rheumatoid arthritis, hematopoietic defects, and fertility preservation.
干细胞是能够自我更新且未分化的细胞类型，可分化为功能细胞。干细胞可根据其来源分为两种主要类型：胚胎干细胞和成体干细胞。干细胞还可根据分化潜能的范围分为全能干细胞、多能干细胞、多潜能干细胞和单能干细胞。多潜能干细胞能够分化为某一特定谱系内的所有细胞类型。多潜能干细胞有诸多优势和用途。多潜能干细胞在发育、组织修复和保护过程中起着关键作用。多潜能干细胞已被应用于治疗多种疾病，如脊髓损伤、骨折、自身免疫性疾病、类风湿性关节炎、造血缺陷和生育力保存。
