Morris Brian J, Waskett Jake H, Gray Ronald H, Halperin Daniel T, Wamai Richard, Auvert Bertran, Klausner Jeffrey D
School of Medical Sciences, University of Sydney, Sydney, Australia.
Circumcision Independent Reference and Commentary Service, Radcliffe, Manchester, UK.
J Public Health Afr. 2011 Sep 5;2(2):e28. doi: 10.4081/jphia.2011.e28.
Despite over two decades of extensive research showing that male circumcision protects against heterosexual acquisition of HIV in men, and that includes findings from large randomized controlled trials leading to acceptance by the WHO/UNAIDS and the Cochrane Committee, opponents of circumcision continue to generate specious arguments to the contrary. In a recent issue of the , Van Howe and Storms claim that male circumcision will increase HIV infections in Africa. Here we review the statements they use in support of their thesis and show that there is no scientific basis to such an assertion. We also evaluate the statistics used and show that when these data are properly analyzed the results lead to a contrary conclusion affirming the major role of male circumcision in protecting against HIV infection in Africa. Researchers, policy makers and the wider community should rely on balanced scholarship when assessing scientific evidence. We trust that our assessment may help refute the claims by Van Howe and Storms, and provide reassurance on the importance of circumcision for HIV prevention.
尽管二十多年来广泛的研究表明,男性包皮环切术可预防男性通过异性性行为感染艾滋病毒,这其中包括大型随机对照试验的结果,这些结果促使世界卫生组织/联合国艾滋病规划署以及科克伦协作网予以认可,但包皮环切术的反对者仍继续提出似是而非的相反观点。在最近一期的某刊物中,范·豪和斯托姆斯声称男性包皮环切术会增加非洲的艾滋病毒感染率。在此,我们审视他们用以支持其论点的陈述,并表明这种断言毫无科学依据。我们还对所使用的统计数据进行评估,结果表明,当对这些数据进行恰当分析时,得出的结论恰恰相反,即肯定了男性包皮环切术在预防非洲艾滋病毒感染方面的主要作用。研究人员、政策制定者及更广泛的群体在评估科学证据时应依赖全面公正的学术研究。我们相信,我们的评估或许有助于驳斥范·豪和斯托姆斯的说法,并让人对包皮环切术在预防艾滋病毒方面的重要性放心。