Antibacterial Activity of Metabolites Products of Isolated from Sponge sp. Against .

The objective of this study was to investigate the antibacterial activity of primary and secondary metabolites from isolated from sponge sp. against . A descriptive method was used in this research. The antibacterial activity was analysed by paper disk method. The results showed that the primary metabolites produced by that is in symbiosis with sponge sp. were able to effectively inhibit growth with an inhibition zone diameter of 12.9 mm, while the secondary metabolites of 9.9 mm. Electrophoresis analysis of the primary metabolites showed that there were 11 protein bands which were not found in secondary metabolites. Protein bands with low molecular weights presumably had an inhibiting effect on the growth of .