Sugita H, Matsuo N, Hirose Y, Iwato M, Deguchi Y
Department of Marine Science and Resources, Nihon University, Kanagawa, Japan.
Appl Environ Microbiol. 1997 Dec;63(12):4986-9. doi: 10.1128/aem.63.12.4986-4989.1997.
Vibrio sp. strain NM 10 with an inhibitory activity against Pasteurella piscicida K-III was isolated from the intestine of a spotnape ponyfish (Leiognathus nuchalis). This bacterium efficiently produced an antibacterial substance after growth at 20 degrees C for 24 h on 1/5 PYBG agar prepared with 50% seawater at pHs of 7.5 to 9.0. The antibacterial substance was heat labile and proteinaceous, with a molecular mass of less than 5 kDa, possibly a bacteriocin or a bacteriocin-like substance.
从斑颈叶鲹(Leiognathus nuchalis)的肠道中分离出了对杀鱼巴斯德氏菌K-III具有抑制活性的弧菌属菌株NM 10。该细菌在由50%海水制备的pH值为7.5至9.0的1/5 PYBG琼脂上于20℃培养24小时后,能高效产生一种抗菌物质。该抗菌物质对热不稳定且为蛋白质类,分子量小于5 kDa,可能是一种细菌素或类细菌素物质。