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肝脏上皮样血管平滑肌脂肪瘤:一例报告

Epithelioid angiomyolipoma of the liver: a case report.

作者信息

Lee Soo Yeon, Kim Baek-Hui

机构信息

Department of Pathology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.

出版信息

Clin Mol Hepatol. 2017 Mar;23(1):91-94. doi: 10.3350/cmh.2017.0011.

Abstract

Epithelioid angiomyolipoma (EAML) of liver is a rare neoplasm. Hepatic EAML is often misdiagnosed as other neoplasms such as hepatocellular carcinoma due to non-specific clinical and radiologic features. The morphologic features under microscope and immunohistochemistry staining profile are important in the diagnosis EAML. Here, we report a case of 52-year-old man who found 1.2 cm mass in liver by routine checkup. On the impression of hepatocellular carcinoma, lateral sectionectomy of the liver was done. Microscopically, the tumor is composed of predominant epithelioid cells with vascular component and foamy cells. These cells were positive for HMB45, MelanA, and smooth muscle actin and negative for epithelial membrane antigen. The final diagnosis was hepatic EAML.

摘要

肝脏上皮样血管平滑肌脂肪瘤(EAML)是一种罕见的肿瘤。由于临床和影像学特征不具特异性,肝脏EAML常被误诊为其他肿瘤,如肝细胞癌。显微镜下的形态学特征和免疫组化染色特征对EAML的诊断很重要。在此,我们报告一例52岁男性,通过常规体检发现肝脏有一个1.2厘米的肿块。基于肝细胞癌的诊断印象,进行了肝脏外侧段切除术。显微镜下,肿瘤主要由上皮样细胞、血管成分和泡沫细胞组成。这些细胞HMB45、MelanA和平滑肌肌动蛋白呈阳性,上皮膜抗原呈阴性。最终诊断为肝脏EAML。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3d2/5381838/0a4bafd7bd36/cmh-2017-0011f1.jpg

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