Department of Chemistry & Biochemistry University of California , Santa Barbara, California 93106, United States.
J Org Chem. 2017 Mar 17;82(6):2806-2816. doi: 10.1021/acs.joc.7b00010.
The case is made for transitioning organic chemistry from a developed discipline that remains highly dependent upon organic solvents to one that will be sustainable, based on water as the reaction medium. Processes in hand that today achieve the same bond constructions characteristic of traditional organic synthesis, but can be accomplished under environmentally responsible conditions, are discussed as representative of the potential that lies ahead.
该案例主张将有机化学从一个高度依赖有机溶剂的发达学科转变为基于水作为反应介质的可持续学科。本文讨论了目前能够实现传统有机合成特征键构建的在手过程,但可以在环境负责的条件下完成,这些过程代表了未来的潜力。