近红外光谱作为临床病情恶化的预测指标：两例导管依赖型先天性心脏病婴儿的病例报告
Near-infrared spectroscopy as a predictor of clinical deterioration: a case report of two infants with duct-dependent congenital heart disease.
作者信息
Mebius Mirthe J, du Marchie Sarvaas Gideon J, Wolthuis Diana W, Bartelds Beatrijs, Kneyber Martin C J, Bos Arend F, Kooi Elisabeth M W
机构信息
University Medical Center Groningen, Beatrix Children's Hospital, Division of Neonatology, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
University Medical Center Groningen, Center for Congenital Heart Diseases, Pediatric Cardiology, Beatrix Children's Hospital, University of Groningen, Groningen, The Netherlands.
出版信息
BMC Pediatr. 2017 Mar 16;17(1):79. doi: 10.1186/s12887-017-0839-3.
BACKGROUND
Some infants with congenital heart disease are at risk of in-hospital cardiac arrest. To better foresee cardiac arrest in infants with congenital heart disease, it might be useful to continuously assess end-organ perfusion. Near-infrared spectroscopy is a non-invasive method to continuously assess multisite regional tissue oxygen saturation.
CASE PRESENTATION
We report on two infants with duct-dependent congenital heart disease who demonstrated a gradual change in cerebral and/or renal tissue oxygen saturation before cardiopulmonary resuscitation was required. In both cases, other clinical parameters such as heart rate, arterial oxygen saturation and blood pressure did not indicate that deterioration was imminent.
CONCLUSIONS
These two cases demonstrate that near-infrared spectroscopy might contribute to detecting a deteriorating clinical condition and might therefore be helpful in averting cardiopulmonary collapse and need for resuscitation in infants with congenital heart disease.
背景
一些患有先天性心脏病的婴儿存在院内心脏骤停的风险。为了更好地预测先天性心脏病婴儿的心脏骤停，持续评估终末器官灌注可能会有所帮助。近红外光谱法是一种连续评估多部位局部组织氧饱和度的非侵入性方法。
病例报告
我们报告了两名患有依赖动脉导管的先天性心脏病婴儿，他们在需要进行心肺复苏之前，脑和/或肾组织氧饱和度出现了逐渐变化。在这两个病例中，其他临床参数，如心率、动脉血氧饱和度和血压，均未表明病情即将恶化。
结论
这两个病例表明，近红外光谱法可能有助于检测临床状况的恶化，因此可能有助于避免先天性心脏病婴儿发生心肺功能衰竭和需要进行复苏。
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