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[巯基化合物对胚胎诱导因子的作用]

[Action of sulfhydryl compounds on embryonic inducing factors].

作者信息

Tiedemann Heinz, Tiedemann Hildegard, Born Jochen, Kocher-Becker U

机构信息

Institut für Physiologische Chemie der Freien Universität Berlin, Deutschland.

Heiligenberg-Institut, Heiligenberg, Baden.

出版信息

Wilhelm Roux Arch Entwickl Mech Org. 1969 Dec;163(4):316-324. doi: 10.1007/BF00577018.

DOI:10.1007/BF00577018
PMID:28304474
Abstract

Crude extracts from 9 days old chicken embryos containing neuralizing and mesodermalizing inducing factors as well as purified mesodermalizing factor were incubated with thioglycolic acid and with 2-Mercaptoethanol. The fractions were tested by implanting into early gastrulae ofTriturus orAmbystoma. The mesodermalizing factor is inactivated whereas the neuralizing factor does not lose its activity.

摘要

将含有神经诱导因子和中胚层诱导因子的9日龄鸡胚粗提物以及纯化的中胚层诱导因子与巯基乙酸和2-巯基乙醇一起孵育。通过植入蝾螈或美西螈的早期原肠胚来测试这些组分。中胚层诱导因子失活，而神经诱导因子不失活。

相似文献

1
[Action of sulfhydryl compounds on embryonic inducing factors].[巯基化合物对胚胎诱导因子的作用]
Wilhelm Roux Arch Entwickl Mech Org. 1969 Dec;163(4):316-324. doi: 10.1007/BF00577018.
2
Inducing activity of subcellular fractions from amphibian embryos.诱导两栖动物胚胎亚细胞组分的活性。
Wilehm Roux Arch Dev Biol. 1984 Jan;193(1):1-12. doi: 10.1007/BF00848594.
3
Biological activity of vegetalizing and neuralizing inducing factors after binding to BAC-cellulose and CNBr-sepharose.植物化和神经化诱导因子与BAC-纤维素和溴化氰-琼脂糖结合后的生物活性。
Wilehm Roux Arch Dev Biol. 1978 Dec;184(4):285-299. doi: 10.1007/BF00848387.
4
Proteoglycans with affinity for the neuralizing factor and the vegetalizing factor (activin A homologue).对神经化因子和植物化因子（激活素A同源物）具有亲和力的蛋白聚糖。
Rouxs Arch Dev Biol. 1993 Aug;202(6):316-320. doi: 10.1007/BF00188730.
5
Partially purified factor from embryonic chick brain can provoke neuralization of Rana temporaria and Triturus alpestris but not Xenopus laevis early gastrula ectoderm.从鸡胚脑中部分纯化的因子可诱导欧洲林蛙和高山蝾螈的神经化，但不能诱导非洲爪蟾早期原肠胚外胚层的神经化。
Int J Dev Biol. 1995 Apr;39(2):317-25.
6
[Effect of heterogeneous inducers on the ectoderm of the early gastrula in Rana temporaria in vitro. IV. The inductive effect of embryonic tissue extracts after ribonuclease and proteinase treatment].[异种诱导物对体外培养的林蛙原肠早期外胚层的作用。IV. 核糖核酸酶和蛋白酶处理后胚胎组织提取物的诱导作用]
Ontogenez. 1982;13(6):582-8.
7
[Morphogens: experimental illusion or reality?].[形态发生素：实验错觉还是现实？]
Ontogenez. 1984 Nov-Dec;15(6):563-84.
8
[Isolation and ways of acting of morphogenetic factors during early embryogenesis].[早期胚胎发生过程中形态发生因子的分离及作用方式]
Ontogenez. 1978;9(4):323-32.
9
Evidence that somatotroph differentiation during chicken embryonic development is stimulated by a blood-borne signal.有证据表明，鸡胚胎发育过程中生长激素细胞的分化受到一种血液传播信号的刺激。
Endocrinology. 1995 Sep;136(9):3721-8. doi: 10.1210/endo.136.9.7649077.
10
[The embryonic brain-derived neuralizing factor (EBDNF): its partial purification by ion-exchange and affinity chromatography].[胚胎脑源性神经化因子（EBDNF）：通过离子交换和亲和层析进行部分纯化]
Ontogenez. 1993 Mar-Apr;24(2):24-32.

引用本文的文献

1
A mesoderm-inducing factor from a Xenopus laevis cell line : Chemical properties and relation to the vegetalizing factor from chicken embryos.一种来自非洲爪蟾细胞系的中胚层诱导因子：化学性质及其与鸡胚植物化因子的关系。
Rouxs Arch Dev Biol. 1989 May;198(1):8-13. doi: 10.1007/BF00376364.
2
Biological activity of vegetalizing and neuralizing inducing factors after binding to BAC-cellulose and CNBr-sepharose.植物化和神经化诱导因子与BAC-纤维素和溴化氰-琼脂糖结合后的生物活性。
Wilehm Roux Arch Dev Biol. 1978 Dec;184(4):285-299. doi: 10.1007/BF00848387.
3
Formation of mesodermal pattern by secondary inducing interactions.

本文引用的文献

1
[Not Available].[无可用内容]
Wilhelm Roux Arch Entwickl Mech Org. 1939 Sep;139(3):556-638. doi: 10.1007/BF00578755.
2
[Not Available].[无可用内容]。
Wilhelm Roux Arch Entwickl Mech Org. 1940 Mar;140(1):25-38. doi: 10.1007/BF00576245.
3
[Chemical nature of inductors involved in implant experiments with Triton].[与海卫一植入实验相关的诱导物的化学性质]
通过二次诱导相互作用形成中胚层模式。
Wilehm Roux Arch Dev Biol. 1979 Sep;187(3):231-244. doi: 10.1007/BF00848619.
4
Molecular mechanisms of tissue determination and pattern formation in amphibian embryos.两栖类胚胎中组织决定和模式形成的分子机制。
Naturwissenschaften. 1995 Mar;82(3):123-34. doi: 10.1007/BF01177272.
5
Mesoderm-inducing factors. Their possible relationship to heparin-binding growth factors and transforming growth factor-beta.中胚层诱导因子。它们与肝素结合生长因子及转化生长因子-β的可能关系。
Naturwissenschaften. 1987 Dec;74(12):604-6. doi: 10.1007/BF00368525.
Experientia. 1951 Aug 15;7(8):299-300. doi: 10.1007/BF02150550.
4
[Experiments on the extraction of a mesodermal inductor from chick embryo].[关于从鸡胚中提取中胚层诱导物的实验]
Hoppe Seylers Z Physiol Chem. 1959;314(4-6):156-76.
5
[Experiments on the chemical identification of embryonal induction substances].[关于胚胎诱导物质化学鉴定的实验]
Hoppe Seylers Z Physiol Chem. 1956 Sep 29;306(1):7-32.
6
Effect of trypsin and chymotrypsin on the inducing ability of the kidney and its fractions.胰蛋白酶和糜蛋白酶对肾脏及其组分诱导能力的影响。
Exp Cell Res. 1955(Suppl 3):402-13.
7
[Studies for clarification of the specific capacity of various abnormal inductors in embryonal development of Urodela].[关于阐明有尾目胚胎发育中各种异常诱导物的比容的研究]
Experientia. 1953 Mar 15;9(3):100-1. doi: 10.1007/BF02178336.
8
Late tissue interactions in the segregation of the central nervous system.中枢神经系统分离过程中的晚期组织相互作用。
Ann Med Exp Biol Fenn. 1966;44(2):128-30.