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双胸基因在果蝇腹部中枢神经系统中的功能。

The function ofbithorax genes in the abdominal central nervous system ofDrosophila.

作者信息

Ghysen Alain, Lewis Edward B

机构信息

Laboratoire de Génétique, Université Libre de Bruxelles, 67 rue des Chevaux, B-1640, Rhode St. Genèse, Belgium.

Division of Biology, California Institute of Technology, 91125, Pasadena, Cal, USA.

出版信息

Rouxs Arch Dev Biol. 1986 May;195(4):203-209. doi: 10.1007/BF02438952.

Abstract

We have analysed the influence of the bithorax gene complex (BX-C) on two segment-specific features of the central nervous system ofDrosophila larvae: the "presumptive leg neuromeres" (PLN), which are present only in the thoracic ganglia of the larva and develop into the leg neuromeres of the adult fly during metamorphosis; and the "lateral dots" (LD) which are found in the first abdominal as well as thoracic ganglia. We show in both cases that consecutive BX-C genes can suppress the development of these structures. We also show that each gene is expressed in several consecutive segments, leading to an apparent redundancy of the suppression in posterior segments.

摘要

我们分析了双胸基因复合体(BX-C)对果蝇幼虫中枢神经系统两个节段特异性特征的影响:“假定腿神经节”(PLN),仅存在于幼虫的胸神经节中,在变态过程中发育成成年果蝇的腿神经节;以及“侧点”(LD),存在于第一腹神经节和胸神经节中。我们在这两种情况下都表明,连续的BX-C基因可以抑制这些结构的发育。我们还表明,每个基因在几个连续的节段中表达,导致后段抑制作用明显冗余。

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