Marona-Lewicka D, Michaluk J, Antkiewicz-Michaluk L, Vetulani J
Institute of Pharmacology, Polish Academy of Sciences, Kraków.
Pol J Pharmacol Pharm. 1987 May-Jun;39(3):293-302.
Comparative studies of the laboratory mouse and Acomys cahirinus have shown differences in their motor activity patterns and motor responses to morphine, apomorphine and clonidine. The two species also differed in respect of the density of cerebral alpha 2-adrenergic receptors, but no significant differences between other types of receptors (alpha 1-adrenergic, beta-adrenergic, opiate mu and delta, and spiroperidol binding sites) were found. It is suggested that the high excitability of the Acomys may be related to a deficit in the inhibitory noradrenergic transmission in the central nervous system.
对实验小鼠和埃及刺毛鼠的比较研究表明，它们在运动活动模式以及对吗啡、阿扑吗啡和可乐定的运动反应方面存在差异。这两个物种在脑α2 - 肾上腺素能受体密度方面也有所不同，但未发现其他类型受体（α1 - 肾上腺素能、β - 肾上腺素能、阿片μ和δ以及螺哌啶结合位点）之间存在显著差异。有人提出，埃及刺毛鼠的高度兴奋性可能与中枢神经系统中抑制性去甲肾上腺素能传递的缺陷有关。
