Huang Françoise, van Helden Jacques, Dambly-Chaudière Christine, Ghysen Alain
Laboratoire de Neurobiologie, University Libré de Bruxelles, 67 rue des Chevaux, B-1640, Rhode-St-Genèse, Belgium.
Rouxs Arch Dev Biol. 1995 May;204(5):336-343. doi: 10.1007/BF02179502.
We examine the effect of mutations in theextramacrochaetae (emc) gene on the positioning of macrochaetes on the notum ofDrosophila. We show that, inemc mutants, most of the precursor cells appear earlier than in wild-type individuals, consistent with an antagonizing effect ofemc on the action of the proneural genesachaete andscute. We also show that reducingemc function affects the position of three bristles and/or of their precursors, but has no marked effect on the positioning of the other bristles.
我们研究了extra macrochaetae(emc)基因突变对果蝇背板上大刚毛定位的影响。我们发现,在emc突变体中,大多数前体细胞出现的时间比野生型个体更早,这与emc对原神经基因achaete和scute作用的拮抗效应一致。我们还发现,降低emc功能会影响三根刚毛及其前体细胞的位置,但对其他刚毛的定位没有显著影响。