经典条件作用后家兔CA1锥体神经元突触电位的增强。
Enhancement of synaptic potentials in rabbit CA1 pyramidal neurons following classical conditioning.
作者信息
LoTurco J L, Coulter D A, Alkon D L
机构信息
Section on Neural Systems, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD 20892.
出版信息
Proc Natl Acad Sci U S A. 1988 Mar;85(5):1672-6. doi: 10.1073/pnas.85.5.1672.
A synaptic potential elicited by high-frequency stimulation of the Schaffer collaterals was enhanced in hippocampal CA1 pyramidal cells from rabbits that were classically conditioned relative to cells from control rabbits. In addition, confirming previous reports, the after-hyperpolarization was reduced in cells from conditioned animals. We suggest that reduced after-hyperpolarization and enhanced synaptic responsiveness in cells from conditioned animals work in concert to contribute to the functioning of hippocampal CA1 pyramidal cells during classical conditioning.
与对照兔的细胞相比，在经典条件反射的兔海马CA1锥体细胞中，由高频刺激Schaffer侧支引发的突触电位增强。此外，正如先前报道所证实的，条件反射动物细胞的超极化后电位降低。我们认为，条件反射动物细胞中超极化后电位的降低和突触反应性的增强共同作用，有助于经典条件反射期间海马CA1锥体细胞的功能。
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