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[科特迪瓦风疹血清流行病学。地理分布]

[Seroepidemiology of rubella in the Ivory Coast. Geographic distribution].

作者信息

Ouattara S A, Brettes J P, Kodjo R, Penali K, Gershy-Damet G, Sangare A, Aron Y, Akran V

机构信息

Laboratoire d'Immunochimie, Institut Pasteur, Abidjan, Côte-d'Ivoire.

出版信息

Bull Soc Pathol Exot Filiales. 1987;80(4):655-64.

PMID:2830995
Abstract

A total of 3,473 serum samples were collected from healthy subjects in five geographical areas of Côte-d'Ivoire, between July 1985 and August 1986, and were analysed for the presence of rubella haemagglutination inhibition antibodies. Rubella antibodies were present in 1,994 of the samples giving a prevalence of 57.4%. The distribution of this prevalence appeared to be influenced by the climatic conditions and the density of population. The areas of Korhogo and Sinematiali in the north with a hot and dry climate had high prevalences, while the areas of Bouake and Bondoukou in the Centre and Centre-east respectively had low prevalences. The prevalence of rubella antibodies increases with age until it reaches a relatively low level from the age of 15 onward. The analysis of the data by the chi 2 test indicates that there was a statistically significant variation in the prevalence of rubella antibodies between urban and rural communities (p less than 0.001). In the areas of Korhogo and Sinematiali the rubella virus appeared to be best circulate in the rural communities, while the reverse was observed in the areas of Bouake and Bondoukou. In this study, there was not a sex influence in immunity to rubella, because no difference immunity to the virus was observed between males and females. In women of child-bearing age (15 to 44 years) the rubella immunity was relatively low (61.2%).

摘要

1985年7月至1986年8月期间,从科特迪瓦五个地理区域的健康受试者身上共采集了3473份血清样本,并对其中风疹血凝抑制抗体的存在情况进行了分析。1994份样本中存在风疹抗体,患病率为57.4%。这种患病率的分布似乎受到气候条件和人口密度的影响。北部气候炎热干燥的科霍戈和锡内马蒂亚利地区患病率较高,而中部和中东部的布瓦凯和邦杜库地区患病率较低。风疹抗体的患病率随年龄增长而增加,直到15岁以后达到相对较低的水平。通过卡方检验对数据进行分析表明,城市和农村社区风疹抗体的患病率存在统计学上的显著差异(p<0.001)。在科霍戈和锡内马蒂亚利地区,风疹病毒似乎在农村社区传播得最好,而在布瓦凯和邦杜库地区则观察到相反的情况。在这项研究中,风疹免疫不存在性别影响,因为在男性和女性之间未观察到对该病毒的免疫差异。在育龄妇女(15至44岁)中,风疹免疫力相对较低(61.2%)。

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